New Drug Trials: Just found this on the... - PBC Foundation

PBC Foundation

9,465 members8,261 posts

New Drug Trials

Ginger_11 profile image
0 Replies

Just found this on the Canadian PBC website, possible conclusions to new drug at end of April 2014: DOUBLE-BLIND PHASE OF INTERCEPT’S PHARMACEUTICALS

PHASE III TRIAL OF OBETICHOLIC ACID (OCA) IN PBC.

Also, the international POISE project for PBC :

Intercept Announces Positive Pivotal Phase 3 POISE Trial Results. NEW YORK, March 16, 2014 (GLOBE NEWSWIRE) -- Intercept Pharmaceuticals, Inc. (Nasdaq:ICPT) (Intercept) today announced that its international Phase 3 POISE trial of obeticholic acid (OCA) for the treatment of primary biliary cirrhosis (PBC) demonstrated that OCA, at both a 10 mg dose and a 5 mg dose titrated to 10 mg, met the trial's primary endpoint of achieving a reduction in serum alkaline phosphatase (ALP) to < 1.67x ULN with a ≥ 15% reduction from baseline and a normal bilirubin level after 12 months of therapy. The proportion of patients meeting the POISE primary endpoint was: 10% in the placebo group, 47% in the 10 mg OCA group and 46% in the 5-10 mg OCA group (both dose groups p < 0.0001 vs placebo) in an intention to treat .................. etc etc

(Seems there is now another drug which will be available in the near future)

ir.interceptpharma.com/rele...

Written by
Ginger_11 profile image
Ginger_11
To view profiles and participate in discussions please or .
Read more about...

Not what you're looking for?

You may also like...

March 2014 - Passing along a 'good news' link to a press release supporting improvements with Obeticholic Acid (OCA) in patients with PBC

I'm sharing information I ran across today in regard to clinical trials with Obeticholic Acid or...

I ran across this information today and wanted to share in case you are interested: New PBC Research Trial / UK and US

NEW PBC RESEARCH Lumena is an early stage biotech company focused on better treatment options for...

Trials for new drug in uk

Hi haven't posted in awhile as I have not had much contact with my Dr at all about the condition...

Should be Sceptical with OCA?

Sorry... first, I don't want to make People unnecessarily scared especially because of my very...

Maybe I shouldn’t post OCALIVA side effects. I’m hoping everyone here knows them

MEDICATION GUIDE OCALIVA (o-CAL-eh-vah) (obeticholic acid) tablets What is the most...