Neuroimaging revealed abnormal hyperintense signals in the cerebellum and dorsal and lateral columns of the spinal cord, and obstructive hydrocephalus. A biopsy of the stomach revealed chronic gastritis, intestinal metaplasia, and atrophy. After 3 months of initiating methylcobalamin therapy, significant improvement was noticed clinically, and brain magnetic resonance imaging was near to normal.
Conclusions
This study was novel in reporting subacute combined degeneration of the spinal cord and hydrocephalus associated with vitamin B12 deficiency in adults.
Pub med This study was novel in reporting subacute combined degeneration of the spinal cord and hydrocephalus associated with vitamin B12 deficiency in adults
Hiya, thanks for sharing........Gosh thats crazy! Wow, did he have symptoms similar to B12 deficiency? Did they try B12 injections? Are you on regular B12 injections?
It would be difficult to say because of his overall medical condition and this was in the early 70s when I had never heard of B12 diff or PA in fact I had never heard of it until I was diagnosed . ( Although I have since discovered through doing my family history that my maternal grandmother died from PA in her mid 50s) Yes I self inject every 3 to 4 weeks after not getting anywhere with my present surgery who were only happy to prescribe the once every 3 month jab
No I only have B12 and folate tested. My GP put me on B12 injections due to my multitude of symptoms and family history. I documented things and flagged to GP. I did have to change GP surgery to be heard and initially the New surgery also said no, but then the next day Dr tsaid they spoke to someone and I was to be put on B12 injections immediately. I was lucky with the second GP surgery. Most people are still struggling
This seems related to folate and B12 deficiency. Flour is fortified with folic acid in many countries, such as Australia and Canada, and has proven an effective way of reducing neural tube defects in babies. But folic acid is not the active form so not everyone can convert it to active form. those with MTHFR genes cannot and alot of people have this. My understanding is if someone has B12 deficiency, then this should be addressed before folate deficiency else it can lease to damage to the spinal cord.....this may explain what happen to your son if you were B12 deficient and it was undiagnosed. I think my B12 deficiency was masked for longer as I took folic acid supplements as advised.
youtube.com/@B12dTalks/videos There are lots of good talks on the B12d.org You Tube channel, including the one below...
Understanding the complexities and central role of B12 in health and life - Dr David Morris NHS GP vimeo.com/891099138/4150efa...
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Could posterior cord syndrome be a B12 problem?
Spinal stenosis & b12 deficiency 
Why cyanocobalamin?
The Royal 
