I have not been treated well by my GP. I am symptomatic for B12 deficiency as well as a family history of PA (4 generations). My GP will not give me the Holo-TC test, only the standard B12 test which, as you are all aware is more than useless when you suspect server B12 deficiency.
The latest test results that I pushed for was ANA. This test result was withheld from me for nearly 11 months. It showed speckling on the Hep-2 cells under immunofluorescence. I pushed for more tests, following the symptoms and subsequent test results. About 2 weeks ago I received a positive AMA M2. My doctor then sent me a message! (Disgusting) On the Ask my GP platform to inform me that I had PBC. The shock would have been too much for some people, and I truly believe that this information should have been given during a face to face appointment.
But, due to my chronic ill health I took this in my stride as I've been constantly gaslit by the medical profession. Anyway, I've researched this diagnosis and found a link towards PA and mimicry on a cellular level to the Biliary ducts. Also high dose Omeprazole prescribed for over 14 months to reduce my stomach acid has not helped as this is another factor that can cause PBC and facilitate in the destruction of both Bile duct epithelial cells and parietal cells as they mimic eachother, the body attacks them both with the same furosity.
I was not told about this as a likely outcome of Omeprazole and I was never offered liver screening.
I now feel like a ticking bomb. I do not know what stage I am at with PBC as my GP has gone radio silent.
I will attach some interesting reading for everyone with regards to PA &B12 deficiency, Omeprazole and PBC, along with liver disease in general. I also have a fuller explanation on the causation that I will try to upload or put a link to later.