Folate/Folic acid supplement - Pernicious Anaemi...

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Folate/Folic acid supplement

Chickens44 profile image
4 Replies

I have been using Folic Acid 5mg oral supplement EOD since starting b12 injections just over three weeks ago. I was getting some loose bowel, so was advised to try Methylfolate every day instead. However I am wondering if I should be using injectable Folic 5mg instead. My problem is malabsorption due to low stomach acid after using PPIs for too many years, probably plus a dose of entonox in 2019.

Any thoughts?

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Chickens44
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4 Replies
Technoid profile image
Technoid

Folate absorption can be reduced with lower stomach acid so an injection could be an option if folate is not coming up. If you are injecting I would definitely not use 5mg folic acid but more like 800mcg of one of the natural forms, so it can get to work right away without conversion or unmetabolized folic acid build-up.

Nackapan profile image
Nackapan

I was prescribed high dose folate with iron. Terrible diarrhoea.

Only take for one day

I only needed 400mcg of folic acid.

3 months later folate went from 5 to above 2o ( lab didn't measure higher than that ) Diarrhoea coujx be caused by the high dose alone!

Go by blood results.

Alter food intake perhaps.

Many cereals and other foods are fortified

EiCa profile image
EiCa in reply to Nackapan

Hi Nackapan,

Did you mean you only took the high dose folate with iron once?

Nackapan profile image
Nackapan in reply to EiCa

Yes But then took ferrous fumarate 210

And 4oo mcg folic acid separately

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