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Son tested positive for gastric parietal cell antibodies

fatfatfat profile image
4 Replies

My son has history with h pylori, which he was treated for, but the symptoms haven't gone away completely.

Last week I was talking about my own b12 deficiency and he informed me he has the same symptoms. I know he has been more tried than normal, but I put it due to the h pylori, after effects. As that is what his specialist alluded to. Luckily, his specialist also referred him on to see another specialist (due there in July).

When my mother heard about this, she collected some money and said get him seen privately. His b12 wasn't checked but his gastric parietal cell antibody was positive. His allergy test was also high, which they now want test further for.

Does having gastric parietal cell antibodies, always mean pernicious aneamia?

I been told to pick up a blood test form for Monday, from the gp yesterday. They need to do their own test, I been told. I don't really want injections for my 10 year old. But if he needs it, he needs it.

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4 Replies
Nackapan profile image
Nackapan

Parietal cell antibody test is not used to diagnose Pernicious Aneamia .Indicative of many other things .

The Intrinsic factor antibody test is .

If positive he has PA and will need regular b12 injections.

If negative still doesn't rule PA as some need a few tests for antibodies to be detected

His B12 levels need to be checked.

Serum or active tests are available .

Also folate ,vit D ,iron would've hopefully been done.

B12 if needed should be given before folic acid if needed .

You are probably aware of this if b12 deficient /PA yourself .

Suprised not done if H-pylori being treated.

You ard right, that coursrs of antibiotics can exhaust you.

If his diet is varied and includes diary ,meat ect and his b12 levels are low even after h-pylori is cleared he must have sn absorbtiin problem.

Have the tests done before oral tablets of b12 are given .

Hope you get to the bottom of things.

Good to log his symptoms.

Don't worry if he does need b12 injections.

Diabetics cope.

Also better than irreversible damage being done.

Subcutaneous b12 just ax effective as IM in my experience.

Ask for all the relevant tests to be put on his blood form.

Check it.

.

fatfatfat profile image
fatfatfat in reply toNackapan

Sorry I wrote a long reply last time, I guess it didn't post. I'm fairly new at pa diagnosis. I got tested and was told I was pa last month. It was in March I first got diagnosed with megaloblastic anaemia due to b12 deficiency. Then followed up with pa diagnosis.

My son gp sent him for a long list of things to check. The blood test was just done today. Took a while to get blood test appointment.

If he needs medication I would of course give it to him. I was just feeling sad when I wrote the first post.

I deeply appreciate your reply. Thank you

am111 profile image
am111

Your son's B12 levels should definitely be checked. H.pylori bacteria can definitely affect the stomach lining and hence, absorption of B12.

Oral B12 also works for people who do not have a significant B12 deficiency. Something like 1000mcg/day works, so injections may not be needed.

fatfatfat profile image
fatfatfat in reply toam111

Thank you for the reply. If he dose need it, I hope oral would work for him. Getting him to do the blood test was hard enough. Need to wait 7 working days for results now.

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