I was diagnosed with under active thyroid in 2021 which I’m still struggling daily with. I have peripheral neuropathy in legs and can’t walk far at all and I’ve just turned 40.
My B12 at the time of thyroid diagnosed with not being on any supplements was 379.8 (197-771)
I’ve been supplementing b complex and b12 liquid by nature provides. This boosted my b12 to 500 mark.
I was wondering if the injections would benefit me more. Ive not tried them before and a bit nervous as when I first started b12 it made me a bit jittery but that subsided. I would like to try the methylcobalamin (methylated B12).
Does anyone know any suppliers or german suppliers I can purchase these from or how I could feel after trying them?
thank you 😊
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Denny39
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One used to be able to obtain Methylcobalamin from Arnika manufacturing pharmacy in Munich . But I believe they do not supply anymore . Methylcobalamin is expensive .I tried it a few years ago and found it no more beneficial than hydroxocobalamin. But we are all different . A possibility is buying powdered Methylcobalamin from Oxford Biosciences and rehydrating it with saline ( only obtained from German online pharmacies . )
Hello, I too have hypothyroidism and use nature provides B12 drops. Plus Methyl B12 from Oxford Bio Sciences and Hydroxy s.i.
As wedgewood says, we all react differently, but injections are certainly better than sublingual drops, and Methylcolbamin is recommended for neurological symptoms. It works for me
Here is link for Oxford Bio Sciences, their Resources section recommends needles and saline .
From Summary of BSH Cobalamin and Folate guidelines
" In the presence of discordance between the test result and strong clinical features of deficiency, treatment should not be delayed to avoid neurological impairment"
This is where there is plenty of B12 in the blood but it's not getting to where it's needed in the cells. MMA, homocysteine and Active B12 (holotranscobalamin) tests may help to diagnose Functional B12 deficiency.
I urge UK forum members to track down the local B12 deficiency guidelines used by their ICB (Integrated Care Board)in England or Health Board in Wales/Scotland and then compare them with NICE CKS link up page.
If you can't find them online or by searching forum posts here then best bet is to submit a FOI (Freedom of Information) request to ICB/Health Board asking which B12 deficiency guidelines they are using and for a link to or copy of them.
If diet is B12 rich, symptoms of B12 deficiency are likely to be caused by an absorption issue in gut.
If a GP suspects an absorption issue, I would expect them to at least test for PA and coeliac disease.
It's vital to get adequate treatment. Delayed or inadequate treatment can increase the risk of developing permanent neurological damage. In severe cases the spinal çord can be affected.
If you are symptomatic for B12 deficiency and GP is reluctant to treat then may be worth showing them the PAS leaflet below as it discusses serious consequences of untreated B12 deficiency.
PAS leaflet SACD, sub acute combined degeneration of the spinal cord
Table 1 in above article is about frequent misconceptions about B12 deficiency that health professionals may have.
There's more info in pinned post "Various PA/B12D resources".
I'm not medically trained.
I was forced to treat myself when NHS refused to treat me despite over 50 typical symptoms of B12 deficiency. All but one of my serum B12 results were well within range.
What makes you think your peripheral neuropathy is caused by B12D? It can be caused by many other things - kidney or liver diseases, infections and being overweight just to name a few.
Had a nerve conduction study privately and that was normal.
It only started when I started thyroid medication. I just posted a new post with some blood ranges on. If you kindly don’t me looking at that and letting me know what you think of my numbers old and new. Thanks
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