Postpartum depression

[WiscGuy]

A recent release described a newly-developed drug for postpartum depression. Effects of the drug are said to last 45days. Cost is greater than $10,000 USD. No mention was made at all of nutrients.

I seemed to recall a connection between postpartum depression and B12; a quick search on regular Google came up with these two articles (there probably were others, but I stopped looking):

2012

ncbi.nlm.nih.gov/pmc/articl...

2021

ncbi.nlm.nih.gov/pmc/articl...

Why is there such hubbub about a new drug that delays postpartum depression symptoms for 45 days at a cost exceeding $10,000, and no mention of nutrients? I don't know for sure, but assume the prevalence of a market-based, profit-motive research model might have something to do with it.

[EyesWideNow]

Hello, there is a major link with postpartum depression and B12 deficiency apparently. I read a few months ago that during pregnancy the mum’s B12 stores are concentrated and sent through the placenta to ensure a 2 yr supply to the baby-stored in the brain predominantly. This is to last until weening and brain development and growth obviously use these stores up to varying degree. I’m assuming this could leave new mums quite vulnerable to B12 deficiency and hence depression. Then after a month or so later there was an article in uk national news declaring that NHS were looking to remove ‘Entonox (gas and air) from maternity suits. Not that it wasn’t perfectly safe for pregnant mums but as they thought it wasn’t good for midwives to be exposed to it long term. There has also been a ban on NOX canisters used for things like whipped cream etc as there is a problem of substance abuse in inhaling the gas. Leaving a lot of abusers in a very sorry state if they even survive their ‘addiction’-as it destroys B12 stores? The thing is though that already in a vulnerable state, still carrying baby no less, mums have been probably universally given ‘harmless’ Entonox’ as the first line choice of pain control and unknowingly stripped their last remaining stores of B12! I have been searching and searching but still can’t find a reference to verify if Entonox passes the placenta or not potentially stripping the baby’s newly acquired B12 stores too!!!!!! Anyone know? Please let me know. I have a daughter with Autism and have studied far and wide for reasons/causes etc and I know she is PA but doubt she was born that way x

[Hectorsmum2 in reply to EyesWideNow]

During my second pregnancy I had entonox several times in regard to an injured knee that kept locking. My baby was unable to feed once born and has multiple health issues, dyspraxia and autism. I wonder if the huge rise in cases of autism is down to B12 deficiency. I think gas and air started being used in late sixtys when the rise in autism numbers started. I was depressed after he was born as well.

[EyesWideNow in reply to Hectorsmum2]

Hello, I battled for years to come up with any answers and my first thought was vaccines and then B12 and then realised that the reason for people blaming vaccines could be linked in. The vaccines have been given combined which is an awful lot to take for a baby and that surely causes a response of increasing homocysteine levels that can only be reversed by-you guessed it-B12. So although vaccines can be beneficial, when they are combined or produced in a lab with less than adequate health and safety measures in place ( like most are -tests on GP fridges showed some extremely contaminated supplies with mold, metal and glass etc) then just as a baby needs all of the B12 in place for neurological development etc it has been affected by 2 sources of disturbance affecting those B12 stores. My theory anyway and I haven’t found anything disproving that yet? I’m just glad that both my and my daughter’s nutrition was decent through early years as there is a theory that some of those problems can be alleviated going through puberty as the brain ‘rewrites’ itself if there are adequate supplies of B12 etc in place? Seemed to have worked for me looking back and definitely for my daughter? Hopefully science can find the answers sooner rather than later eh?! 🤞

[WiscGuy in reply to EyesWideNow]

You mentioned an interest in possible links between B12 and autism. This link is to search results on Google Scholar (a research-database search engine) for the search terms "B12 autism":

scholar.google.com/scholar?...

[EyesWideNow in reply to WiscGuy]

Thank you so much!!!! I have downloaded it to read and digest at my leisure. It looks exactly the sort of research I’m interested in. This sounds gruesome but I read that in autopsy it was very obvious who was autistic by the B12 storage in the brain tissue and that intrigued me into further research articles some years ago. This seems to explain the over and under stimulation issues with the myelin sheaths etc and how it affects pain reception etc sooooo interesting 🙏🥰🙏

[EyesWideNow in reply to WiscGuy]

Again-I can’t thank you enough for this link. For personal reasons I have to be a bit careful of websites and hacking etc so it slows me down a bit but these findings verify all and more that I’d thought. OMG the work has been done with research but probably poorly funded etc it is truly shameful and criminal what is happening and being perpetrated by companies and organisations who profess and are paid handsomely to keep nations healthy. They should maybe be a bit more honest and market themselves as profitable population control specialists 🤬

[MrsTuft]

I had horrific PND. Makes me wonder…

[Ghound in reply to MrsTuft]

Me too !

[OldmanD]

There is money to be made in a drug that costs 10,000usd and nothing to be made with B12 and no one not doctors, not ordinary folks will believe a thing about B Vitamins . . .It has to be some up market overpriced hubbub. . . . . I have not read here of anyone wanting Cyano instead of hydroxo or methyl but endless posts about wanting Hydroxo or Methyl. . . . . I often dont have such a choice . . . . . . Budget is limiting. . . . . . i;ll ad a little bit. . . . . . 10,000 over 45 days I think . . . . . . That would be $220 per day. . . . . That could take a bit of the rough edge off things for some. . . . . Or near enough 10 years of daily B12 jabs. . . . . .