Mcas and Pa questions

[SickNessa]

I have Sub Acute Degeneration of spine from b12d as well as MCAS. I have always been sensitive to shots and I do react to them.

should I keep taking them? What shall I do if I cannot keep taking them?

I am worried of dying and my MCAS is severe.

[jade_s]

Hi SickNessa, what kind of reaction do you get to the shots?

Is it an allergic-type reaction, i.e. anaphylactic reaction? Has been determined that it's an allergy to the cobalt? If so, there is a desensitization protocol that involves starting with injecting smaller amounts and gradually work your way up. I gave several references in this post : healthunlocked.com/pasoc/po...

It can also be an allergy to the other compounds in the solution, e.g. preservatives. Have you tried different brands or types? What brand/form of B12 do you use now?

[Galixie in reply to jade_s]

MCAS isn't quite the same as an allergy. The reactions are allergic type reactions, but they are not caused by IGE allergies. Instead the mast cells in the body behave abnormally and degranulate (causing the allergic type reaction) to benign things that the person is not actually allergic to. And, just to make things more complicated, something that triggers a reaction one time may very well not trigger a reaction another time. Or it can consistently cause a reaction, even though there is no true allergy to it. And reactions can go from mildly annoying to life-threatening without warning, so it's kind of a scary thing. I'm not the OP, so I don't know what kind of reactions they've been getting, but a desensitization protocol may not work the way it would for someone with an IGE allergy.

If the reactions have, thus far, not been life-threatening, I think what I would do in that situation is to only have an injection when someone is available to watch over me and potentially administer epinephrine if the reaction became severe. But, of course, a discussion with your doctor about it is probably the best first step.

[am111]

You might be able to switch to high-dose orals in case you are allergic to shots. It is not the best solution, but in the case of reaction to shots, this might be the only alternative.

[Suffering_sunny]

Did you get this figured out?

I am in the position where b12 and folic acid have made me feel like hell for 3 months solid now... and I have suspected MCAS.

I stopped my injections 10 days ago, and I do not know what to do.