Hi , new member : Just a quick question... - Pernicious Anaemi...

Pernicious Anaemia Society

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Hi , new member

wp69 profile image
wp69
4 Replies

Just a quick question , is pernicious anemia related liver problems , as ive got both , but leading a quite normal life without many issues , thanks , Will.

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wp69
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4 Replies
Nackapan profile image
Nackapan

Pernicious anaemia is an autoimmune condition.

B12 is usually stored in the liver

.

Depletes if not enough eaten or can't be used due to absorbtion problems, transit problems or lack of Intrinsic factor to process it.

So in my mind ( non medical) not related to liver problems/ disease)

If that is your query ?

wp69 profile image
wp69 in reply to Nackapan

Yes , I just wondered if there was a link to both , thanks for your reply.

Rexz profile image
Rexz

There are some reports that correlate certain liver conditions to PA but shown to be very rare. I don't profess to understand the correlation or the cause but I do know there are many different causes of liver conditions and seems it may be hard to sort this out if you have both conditions. Additionally, there are autoimmune conditions that attack the liver many people with one autoimmune condition have and will have others. Some are more prevalent than others such as Hashimoto's Thyroiditis of which 40% of those with PA are shown to have.

Here are a couple of reports for your reference:

Pernicious anemia associated with cryptogenic cirrhosis

ncbi.nlm.nih.gov/pmc/articl...

A case of primary biliary cirrhosis associated with pernicious anemia: a case report

casesjournal.biomedcentral....

Hope this helps some.

Rexz

wp69 profile image
wp69 in reply to Rexz

Thank you very much for those links

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