DU Suppression Test and B12

[B12life]

Anyone heard of this test: DU Suppression and have any more recent info on this test?

References provoking my question:

pubmed.ncbi.nlm.nih.gov/642....

and

Nevertheless, in clinical practice abnormal dU suppression serves as a sensitive index of the presence of megaloblastosis due to vitamin B12 or folate deficiency. dU suppression is also abnormal in a number of conditions other than vitamin B12 or folate deficiency, but its overall specificity in detecting tissue dysfunction due to these two deficiency states is considerably higher than that of the serum vitamin B12 or red cell folate levels. - sciencedirect.com/science/a...

[helvella]

I know absolutely nothing about it. But this paper mentions it and refers to the paper you referenced:

Bailey LB, Stover PJ, McNulty H, Fenech MF, Gregory JF 3rd, Mills JL, Pfeiffer CM, Fazili Z, Zhang M, Ueland PM, Molloy AM, Caudill MA, Shane B, Berry RJ, Bailey RL, Hausman DB, Raghavan R, Raiten DJ. Biomarkers of Nutrition for Development-Folate Review. J Nutr. 2015 Jul;145(7):1636S-1680S. doi: 10.3945/jn.114.206599. Epub 2015 Jun 3. PMID: 26451605; PMCID: PMC4478945.

ncbi.nlm.nih.gov/pmc/articl...

[B12life in reply to helvella]

Nice article

[Narwhal10]

Hi B12life,

No, I have never heard of it. Always love to learn though. So, thank you

[Jillymo]

This is an interesting post but just like helvella it is not something I have heard of. It will be interesting to hear what this test reveals so kindly keep us posted with the results.

It is not a test I have heard of being offered in the UK.