In a recent discussion I noticed an interesting point which I had not picked up.
"I am not sure that .... [it in in the interest of PA patients to assert] that passive absorption is completely impossible in patients who have PA - something which flies in the face of all of the evidence - a whole raft of scientific studies and even testimony from one member of the forum who finds high dose oral works for them and was diagnosed as having PA using the Schilling test. "
I had assumed that if you take oral supplements and that they raise your B12 levels then this rules out PA. I did notice a statement somewhere that there is a Cochrane review which says the evidence about oral treatment of B12 is shaky. This could just mean that for many PA has to be treated by injections where in some cases (not properly researched), oral treatment does work for people with PA and also that people whose levels are raised by oral treatment might still have undiagnosed PA.
The Schilling test has disappeared in the UK. Is there a UK (BMJ or NICE) reference that points out that successful oral B12 treatment doesn't rule out PA?
Note: edited by admin