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How long from your first injection did you start to feel better?

huggabugga profile image
9 Replies

Hi, I just started getting B12 injections 1 month ago. I still feel really tired and fatigued. How long will I need to wait to feel normal again?

I have a cyanocobalamin 1,000 mcg injection daily.

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huggabugga profile image
huggabugga
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9 Replies
TravelLulu profile image
TravelLulu

It depends how low your B12 levels were to begin with and how much they need to give to you in a specific amount of time. I had a very high dose initially in a very short amount of time and it actually took approximately a month to finally feel a bit better. So you should start to notice a difference very soon.

jersey-jazz profile image
jersey-jazz

Today I had my eighth B12 shot in eight weeks and, instead of feeling better, I feel really dragged out on the day of the injection. On the whole, though, I think that I feel better over the span of these weeks. I had been going to bed at 3 or 4pm in the afternoon and was often unable to get back out of bed at dinner time. I just stayed in bed. I am just so happy to have been diagnosed and to be getting help.

Gambit62 profile image
Gambit62Administrator

The standard treatment regime really didn't work for me so it wasn't until I started treating myself (actually using a nasal spray whilst waiting for injectable B12 to arrive) that things started to get better - so that was 15 months in my case - and a few more months after that for depression to lift.I did notice the effect of an injection - would have more energy but nothing else was touched for a long time and my balance definitely continued to deteriorate in the 15 months.

Akashrajput profile image
Akashrajput in reply to Gambit62

So you are 100% cured sir ?

MariLiz profile image
MariLiz

I would say it took me several months to really begin to feel the benefit of the injections. I’d got very low, and had one infection after another.

Cherylclaire profile image
CherylclaireForum Support

Not until loading dose injections (2 a week) were reinstated. Three months on that frequency meant that I could finally feel that I was even getting an injection at all - I was starting to doubt that, as I could never feel a thing previously and they seemed to make no difference to my symptoms. Before, I always had to ask the nurses "have you done it yet ?"

We really are all different.

Are you sure that B12 deficiency is your problem, and if it is, is it your only one ?

Some of us have this in common: below/low range folate, ferritin, vitamin D.

Thyroid can also struggle. It can be a tangled web so get these all checked out by a GP.

If you have pernicious anaemia, you might also have other autoimmune problems.

Might be worth having a look at the Pernicious Anaemia Society website - a lot of information there.

Take it easy.

Akashrajput profile image
Akashrajput in reply to Cherylclaire

I've low iron b12 and ferritin

Chucknz profile image
Chucknz

15 years of injections and I'm still exhausted

Akashrajput profile image
Akashrajput in reply to Chucknz

Feel sorry for you 🥺

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