I ran across someone posting on Reddit who has symptoms that might be from B12 deficiency... tingling, fatigue, etc. He's vegan, his serum B12 tested high, but he's taking daily B12 supplements so his serum test might not be accurate.
I recommended trying a B12 shot to see if it helped, but then I remembered that it's best to do testing first... MMA, intrinsic factor... umm, what else? I think I saw a list here somewhere but now I can't find it.
Could someone please point me to the testing list, or even pop over to Reddit to offer a spot of help (reddit.com/r/vegan/comments... )? I hate to see people suffer with B12 deficiency when they don't have to. Thank you!
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genesurf
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Yes, his serum B12 test was accurate. His levels were high because he was taking high-dose oral B12 and has no problems absorbing B12. Injections would be pointless as all they would do would be to raise levels , but in a more painful way.
There are other, more likely, explanations for those symptoms. Perhaps they should see a doctor. And a neurologist for the tingling.
You could try an MMA test, but with sky high levels of B12 its very unlikely that MMA levels would be affected.
My symptoms did not begin to heal until I tried B12 shots, forcing my serum B12 above the top range of the test. No clue why... although lately I've been wondering if maybe my B12 transport was blocked by my methylfolate supplements for MTHFR.
In my case, B12 sublinguals raised my serum B12 into the high range, and MMA, homocysteine, and Spectracell nutrients all looked normal. I saw doctors, saw a neurologist, had an MRI, nerve conduction study, etc. They were no help at all, I was still fatigued and tingling.
Because of the normal tests, I didn't try B12 shots for over a decade. Thank goodness for the online page that said to try B12 shots for all mystery neurological problems no matter what the tests say.
I've found a few other people like me whose symptoms persisted until they used B12 shots. Perhaps once damage has occurred, extra B12 is needed to heal it?
I was able to move to every-other-week SI after dropping my folate to 400mcg/day. And there's this, which I posted and you commented on some time ago: healthunlocked.com/pasoc/po......
It is possible to have Functional B12 Deficiency where there is plenty of B12 in the blood but it's not getting to where it's needed in the cells.
I wonder when he started taking B12 supplements?
If he only started taking them recently it's possible he could have symptoms from a long standing b12 deficiency that could take time to respond to treatment.
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Possible B12 deficiency symptoms
B12 deficiency, injections and blood test results
Confused & could do with some advice please...
B12 Deficiency - GP Only Carrying Out Total Serum Test 
