Severe Itching of Hands and Feet Afte... - Pernicious Anaemi...

Pernicious Anaemia Society

32,244 members23,422 posts

Severe Itching of Hands and Feet After Injecting

Awakeshattered profile image
3 Replies

Hi All

After being diagnosed with PA a year ago and completing loading doses, I began IM injecting when GP would only move from 12 weekly to 10 weekly. This worked well until I suffered severe itching starting at the palms and moving to whole hands and feet, this is mainly at night. I stopped injecting for two weeks, felt ill, began injecting and terrible itching returned. I have done this three times to make sure it is the B12 causing the itching and it seems to be true.

I have used the same pharmacy and the same vials from MyCare.de and have searched the internet but can't find an explanation. I am feeling the need for my injection but the itching doesn't allow sleep.

I understand that if this was a case of too much B12, it wouldn't really cause any significant harm, am I correct in this?

Your expansive knowledge would, as always, be invaluable.

Written by
Awakeshattered profile image
Awakeshattered
To view profiles and participate in discussions please or .
Read more about...
3 Replies
pvanderaa profile image
pvanderaa

Nerve repair if probably the cause of the itching. Goes away faster if you think of it as evidence that you are healing. Anxiety just seems to make it worse and prolongs it. 3 days for the brain to recalibrate to the stronger signals on the nerves. Keep a severity score in a logbook and see if it is less on future injections.

It may actually mean that you need more frequent injections so that you don’t return into a deficient state for B12.

Survivorette profile image
Survivorette in reply to pvanderaa

They tell me IM may not be necessary

pvanderaa profile image
pvanderaa

If you really have PA, then injections will be for the rest of your life. Oral Supplements do not get absorbed in the same way that the B12 recycling mechanism in the gut doesn’t work.

You need to treat by your symptoms as any further blood test should show >1500 pg/ml. Which is what you want to repair the nerve damage. These high results confuse the GP because the guidelines have an upper limit. This upper limit is really only for initial diagnosis.

Since B12 is water soluble, you can’t overdose as you pee the excess away.

You need to be keeping track of all your symptoms in a logbook. Treat the jab as day zero each time and reset the counter, this allows you to compare day 2 to day 2 in a previous cycle to monitor progress over the long run. Repair of nerve damage is very very slow.

You may also like...

Hot hands & feet after months of cold?

doing 1000 sub cutaneous injections, (alternate days for 3 weeks, then 1 weekly so far), possibly...

Increased tingling and burning feet AFTER B12 injections

other people seem to get the same sensations as me after a B12 injection. I seem to get increased...

Hot burning feet after B12 Injections of Cyanaco

deficiency so I received 4 consecutive daily injections of 1000mcg B12 Cyanacobalamin (bad idea,...

Burning lower legs and feet after B12 injection

Hi After my last B12 injection over a month ago I noticed my legs had a burning sensation in the...

Sever dizziness and severe fatigue during walking after four months injection

I inject cyanocobalamin every 4 days for three month but I have developed dizziness and sever...