High b6 related to low folic acid level

[CW12]

Has anyone had high b6 related to low folate levels. My b6 level is 113.6 high without supplements. I was told low folate is probably the cause

[Gambit62 Administrator]

not sure without range how high the B6 levels you have are but basically it is theoretically possible that high B6 could be caused by low folate though I really couldn't say how realistic a scenario that would lead to it is as it would involve dietary intake of B6 being greater than the amounts that the kidneys remove it. I honestly don't know how realistic that would be in the absence of impaired kidney function.

The good news is that although high dose supplementation of B6 over a period of a few months has resulted in neurotoxicity, there have not been any reports of dietary intake resulting in the same.

I haven't been able to find any mention of the scenario in pubmeds literature

[Andrianna]

I also came back with high B6. My result was 266 nmol/L with a reference range of 35-110. Whereas my folic acid was 22 nmol/L with a reference range of 7-46.

I think its so weird that my b6 was so high because I barely took multi-vitamins in 2019. Like maybe 15 pills and thats it.

My doctors say its nothing and are not worried.

[CW12 in reply to Andrianna]

My Dr said the same. And said it is the body’s response to low folic acid

[Andrianna]

I just realized that my melatonin has b6! So ignore my comment. Mine is high because of that!