PPI and PA testing

[Sunnydevon]

Should I stop PPI before PA test?

[fbirder]

If, by a PA test, you mean the Intrinsic Factor antibody test then it shouldn't suffer interference from PPIs.

[Sunnydevon in reply to fbirder]

Thank you. 😊

[Alfabeta]

PPIs are one of the causes of b12 deficiency - look it up under causes on the NHS site.

[Sunnydevon in reply to Alfabeta]

I don’t want to take PPI but have almost constant burning in esophagus. I’m giving it a go for another week (it doesn’t really seem to help) and then I will stop it if no better.

[Alfabeta in reply to Sunnydevon]

Yes, I had the same and was on omaprezole for years and, as a result, became b12 deficient- over three years on I am still suffering. I live without PPI’s now and try to identify the triggers - cheese is the main one for me!

[Sunnydevon in reply to Alfabeta]

Do you avoid a lot of things? Have you tested for PA. I was told I was low on B12 and given loading injections 3 years ago. Since then I have just supplemented.

[Alfabeta in reply to Sunnydevon]

I have to be careful with cheese and go for hard varieties - cheddar is terrible for causing acid. I am a vegetarian so there’s not too many other foods that cause me a problem.

I am told on this site that low stomach acid - a potential cause of b12 deficiency- also causes acid reflux hence using a ppi to cure this makes a deficiency even more likely.

If you are going to get checked for b12, stop taking supplements in good time or you’ll get a false reading.

Good luck.