Having more than 1 B12 injection ?

[Ryaan]

Has anyone who self injects ever injected more than 1 injection just to see how they feel, like if you feel more energetic or if it has a greater effect than a single 1ml injection just as a trial ?

[deniseinmilden]

I'm guessing you mean per day?

I use 1.5mg in 1ml Pascoe brand ampoules every day and a friend uses 2 of these every day (3mg/day) because she has so much neurological damage to repair - which is happening now she is on this rate.

There are several people who need 2 x 1mg hydroxocobalamin injections every day for continued improvement.

Most of us then need quite a lot of extra supplements to support the B12 at this rate of repair.

Unless I get things out of balance and get a serious return of my B12d symptoms, I don't get any additional benefits from taking more than my 1.5mg, even with extra supporting supplements. Once I've had my daily "allowance" of being awake from my body, I just have to give up and go to bed! Sometimes it's 4pm, usually it's 7 to 8 pm! Exceptionally I can do a long day (without it crippling me for weeks). Usually if I want to be awake later then I have to sleep in the afternoon.

For me, what I can do is mostly about balancing my supplements to top up my diet which is focused around the nutrients I need and then making allowance for my autoimmune system - whether it's in a good or bad phase.

Does this answer your question? Hope so!

[Ryaan in reply to deniseinmilden]

Wow........does more than just answer my question.

Very eye opening !

Thankyou

[fbirder]

It’s unlikely to be as effective as having the two injections at separate times.

Any B12 in your blood gets filtered out by the kidney tubule, along with all the other smallish molecules floating around in there. The kidney then reabsorbs all the stuff that it actually wants, including B12. But this reabsorbtion process can only handle a certain amount. Any more than that goes out in the urine.

So if you put a lot in the bloodstream in a short period of time then most of it will just get peed out. If you put the same amount in over two days then some of the first dose will get stored, reducing blood levels. Then less of the second dose will go out in he urine.

It’s why a slow-release method of giving B12 is being investigated. That would enable blood levels to be maintained as high as possible without too much getting wasted by being eliminated.

[wedgewood in reply to fbirder]

Thanks for that good information .

[ACritical in reply to fbirder]

I was told by my privately seen doctor( remember he charges money for the injection), not to have more then 1 injection per day. Not good for your kidneys make them work unnecessarily and most of it then ends up in the toilet.

[Ryaan in reply to fbirder]

Thankyou for your reply.