Megadose of hydroxocobalamin

[topher2018]

After researching the different types of b12 shots I decided to forego ny regular 1000 mcg shot of cyano and try a shot of hydroxo from a private provider. After the shot the provider told me it was a 7 mg shot. This week - a couple days after the shot - I have been quite dizzy and off balance. Any possible connection? This shot was my third weekly loading dose after 5 daily loading doses. So all total I had 5x1000 mcg cyano over the course of about 7 days and then 2 x1000 mcg cyano weekly for two weeks. I also had one shot of 2000 mcg methyl prior to the megadose shot.

[clivealive Forum Support]

Hi topher2018 if you are in the U.K. may I ask where on earth you are getting your cyanocobamalin 1mg injections from?

You are probably urinating most of your megadose shot. I think I had something similar back in 1968 and 1972 when I had two Schilling tests at which time I had a massive B12 injection also had to drink a glass of radioactive B12 and my urine was measured over the next 24 hours or so. Can't remember now whether I felt dizzy but I wouldn't be surprised.

[topher2018 in reply to clivealive]

USA. Standard over here. Do you prefer cyano to hydroxo?

[clivealive Forum Support in reply to topher2018]

I've been on cyano for 46 years and didn't get on with hydroxo. Sadly there is a Europe wide shortage of cyano at the moment.

[Gambit62 Administrator in reply to clivealive]

hi clivealive - surprised to hear about europe wide shortage of cyano - looking at the site I normally use to source my injectable B12 all the cyano seems to be on special offer at the moment so doesn't appear to be any sort of shortage in germany.

[clivealive Forum Support in reply to Gambit62]

My Pharmacist cannot get any, N.I.C.E/NHS have "discontinued" it and the German site recommended to me was still sold out (again) yesterday when I looked.

I have enough till the end of September so hopefully it will became available again before then.

Thanks Gambit62

[topher2018]

The other odd thing is that the dizziness seems to get a bit better (but still there) after I have a sublingual methylcobalamin tablet (1000 mcg). Could a megadose cause my body to purge too much or develop a resistance to b12?

[clivealive Forum Support in reply to topher2018]

I don't know the answer to that - sorry.

It's my bedtime now so I'll bid you goodnight.

[topher2018 in reply to clivealive]

Good night. Thanks Clive.

[fbirder]

So you’ve had about 16 mg over a few weeks.

If they were treating you for cyanide poisoning they would give you 10,000 mg in a single day. Now that is a megadose.

stichtingb12tekort.nl/weten...

[NorthallertonBob]

Ordinary common sense would suggest that if everything was fine and then you started to accept an out of the ordinary procedure and then developed odd symptoms then I would suspect that the new procedure would be the cause of the unwanted side effects.

Try stopping the 'new' treatment' and see what happens.

A bit like saying: I usually drink one bottle of wine in the evening .... but if I have two and a half bottles of wine I feel dizzy. What should I do?

Answer: Go back to one bottle of wine per evening and see if the dizziness goes away.

[Ryaan]

Agree with Northallerton.

Also the excess, your body will get rid of through urine.