Pernicious Anaemia Society
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Vitamin B12 Injections


I am considering self injecting B12.

I am currently taking 5mg folate each day as I was diagnosed deficient.

I have suffered fatigue for many years and just feel so exhausted today.

I am taking oral B12 (the spray) and feel so much better after I have taken it. I don't want to rely on supplements for the rest of my life - I want to address any deeper rooted issues.

I have read that sublingual supplementation of B12 won't affect depleted serum levels. My B12 levels are in the normal range according to blood results - but I am doubtful that is the reality - especially if my folate levels have been low and I have not been aware.

I am right in thinking that injected B12 won't do me any harm aren't I?

If this is the case I would ask for details of where I can get the necessary supplies.

I have increased my intake of green leafy veggies and citrus fruits - I have always eaten loads of eggs and meat,

Thank you in anticipation.

3 Replies

Hi @jacjc you appear to be doing everything right and feeling better for it so why not continue with a healthy "lots of green leafy veggies" for Folate and "loads of eggs and meat" for B12.

Symptoms of a folate deficiency can include:

symptoms related to anaemia

reduced sense of taste


numbness and tingling in the feet and hands

muscle weakness


Are these the sort of symptoms you were having?

There is no danger in self injecting B12 as you cannot overdose on it. However do you really need to as you say you felt so better after the spray and your levels are "normal"? (I hate that word).

Others on here will be able to advise on sourcing B12 from abroad should you decide to do that.

I am not a medically trained person but I've had P.A. (a form of B12 deficiency) for more than 45 years.

I wish you well




Some B12 books I found useful

"What You Need to Know About Pernicious Anaemia and B12 Deficiency" by Martyn Hooper

Martyn Hooper is the chair of PAS (Pernicious Anaemia Society). Book is up to date with UK b12 guidelines.

"Living with Pernicious Anaemia and Vitamin B12 Deficiency" by Martyn Hooper

Has several case studies.

"Could it Be B12?: An Epidemic of Misdiagnoses" by Sally Pacholok and JJ. Stuart (USA authors)

Very comprehensive with lots of case studies.

UK B12 websites

PAS (Pernicious Anaemia Society)

Based in Wales, UK.


PAS tel no +44 (0)1656 769717 answerphone

B12 Deficiency Info website

B12 Deficiency Symptoms


If you're in UK, I'd suggest reading following UK B12 articles/documents.

BSH Cobalamin and Folate Guidelines

Flowchart from BSH Cobalamin and Folate Guidelines

BMJ B12 article



More B12 info in pinned posts on this forum.

"have suffered fatigue for many years"

Have you had tests for Thyroid problems?

Might be worth putting any thyroid results on Thyroid UK forum on HU.

I am not medically trained.


Hi jac , I have my injections from the nurse , but it has to be OK by doc which is a mission as I need it more reg than the 3 months they recommend , I have decided to keep a diary on a daily basis of how I'm feeling and what supplements I'm taking , unfort my auto immune issue , (which they don't understand either ) causes my body to attack the b12 molecule in my stomache , so it can't be absorbed in my stomach , hence why I receive the injections . I haven't been tested for low folic acid , but from advice on here I thought I'd start taking it as some of the symptoms are similar , keeping a diary with anything I'm doing or taking and when and if I start to feel awful again , I'm armed with the reality of

Symptoms to take to the docs .

You appear to be doing everything right , but is worth asking for ur b12 levels to be checked as they aren't done in a routine blood test . Just Incase u have the same issue with absorption in the stomache .




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