High B 12 but deficiency symptoms - Pernicious Anaemi...

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High B 12 but deficiency symptoms

13 Replies

Hi everyone I am new here. I was giving back my lab results with High B 12 of 1494 and low vitamin d. I do not take vitamin b 12 supplements and I do not eat enough meat to have my b 12 that high. I have started to correct the vitamin d deficiency. I was wondering if If anybody had some ideas on why this could be. I eat enough to maintain an average b 12 level. I am suffering depression and anxiety as well. I know b 12 contributes to that.

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13 Replies
Gambit62 profile image
Gambit62Administrator

exactly what symptoms of B12 deficiency do you have.

Was the lab test done by your doctor or privately?

there are a number of conditions that can cause raised B12 - eg liver and renal problems - and lead to a functional B12 deficiency so suggest you speak to your GP and try and get those ruled out.

watermark.silverchair.com/h...

in reply toGambit62

My last lab was done by my gp and he was just like that is normal. I have fatigue, low grade fever, headaches, problems with my gait and memory problems. Blurry visions, numbness, tingling, breathing problems among others .

Gambit62 profile image
Gambit62Administrator in reply to

suggest you print out the article and show it too your GP and ask them to investigate.

Zeebro profile image
Zeebro in reply toGambit62

What article ??

Please share

THanks

Gambit62 profile image
Gambit62Administrator in reply toZeebro

Zeebro ,the one in my first response.

greenbexy profile image
greenbexy in reply toGambit62

The link doesn't appear to be working, maybe because I'm on a mobile?

Zeebro profile image
Zeebro in reply togreenbexy

I also have high B12 and MTHFR Gene. SoO have difficulty with cellular absorbtion.

Maybe you can explain the basis of the article ??

Thanks

fbirder profile image
fbirder in reply toZeebro

Everybody has the MTHFR gene.

Most people have one, or more, mutations in that gene.

Virtually none of those mutations have adverse effects.

The only mutation shown to have adverse effects in some people is homozygous C677>T.

That mutation does not affect cellular absorption of B12.

Zeebro profile image
Zeebro in reply tofbirder

I'm guessing it's a gut issue like IBS or HPylori

Zeebro profile image
Zeebro in reply toGambit62

The Link won't open up. Can you repost it to me ? Thanks

Gambit62 profile image
Gambit62Administrator in reply toZeebro

try this link

academic.oup.com/qjmed/arti...

Zeebro profile image
Zeebro in reply toGambit62

That link worked !

A fascinating and a very complex detailed analysis.

Thank you

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