I've just recently joined the Thyroid community -- I have Hashimoto's and Coeliac -- and was asked to post this query here... Checking back through my B12 tests I can see that I am skipping along the lower 10-20% of the range for B12, and the top 10-20% range for Active B12. I'm in Sydney and testing for Active B12 is standard if B12 is low; see sydpath.stvincents.com.au/t... What is the situation in UK, Canada etc and how are the tests different, and how reliable?
B12 and Active B12: I've just recently... - Pernicious Anaemi...
B12 and Active B12
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Blue_Bee
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Gambit62Administrator
active B12 has one advantage over serum - that it only looks at the forms of B12 that are bound to proteins that allow them to pass into cells.
However, like serum B12 it is still a measure of what is happening in the blood and not what is happening at the cell level - there are different indirect tests that can help with that namely MMA and homocysteine
Blue_Bee - your results are still within the normal ranges on both even if towards top on one and bottom on the other. 5% of people who are off the bottom of the range will actually be okay.
overlap of symptoms with thyroid problems is going to make evaluating symptoms difficult - so MMA might help
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