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blondie2505 profile image
5 Replies

Are you meant to store your hydroxocobalam b12 in the fridge?

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blondie2505
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Gambit62 profile image
Gambit62Administrator

Main problem is light sensitivity - so needs to be somewhere dark.

There is also some temperature sensitivity so it needs to be somewhere cool - though it doesn't actually need to be stored at the temperatures as low as those in the fridge.

blondie2505 profile image
blondie2505 in reply toGambit62

Thank you both

for getting back to me its just the instructions are obviously in German had my dad not left the army when I was a baby and we'd stayed there I wouldn't be having any of these problems.. :-(

fbirder profile image
fbirder

In the dark below 25ºC is what it says on the instructions for all my ampoules. Hydroxocobalamin and cyanocobalamin are quite a bit more stable than methylcobalamin - it's often recommended to store that in the fridge.

Foggyme profile image
FoggymeAdministrator

JamesStone.

@fbirder response to one of your earlier replies:

Re cobalamin and light sensitivity: only the energetic, short-wavelength, light that does any serious amount of phwotodegradation. And amber glass cuts out almost all of that. It's why photographer's dark rooms have red lights - they don't degrade the emulsion in B&W film.

Hydroxocobalamin and cyanocobalamin are much more resistant to thermal degradation. That's why they can be stored up to 25ºC. Methylcobalamin, OTOH, is more thermally labile and many manufacturers recommend storing it in the fridge.

Please note: cyanocobalamin and hydroxocobalamin are easily converted into methylcobalamin and adenyosolcobalamin by most people. Both have been proved to be more stable than methylcobalamin.

The amount of cyanide in cyanocobalamin is absolutely minute (about the amount contained in one prune). clivealive has been using cyanocobalamin for fourth-five years - and no problems there.

Different cobalamins suit different people - it's very an individual 'thing'.

Please stop posting inaccurate and misleading information.

fbirder profile image
fbirder

Methylcobalamin and adenosylcobalamin are unstable and very easily damaged by light. They are therefore unsuitable for use in dietary supplements or pharmaceuticals and are not necessary since they can be formed from cyanocobalamin or hydroxocobalamin within the body. The main form of vitamin B12 found in food is hydroxocobalamin

google.com/patents/US6369041

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