Hashi's, Depression...Could I have PA too?

[Halinka]

Anyone on here with depression who found out that PA was at the heart of the problem? Have Vit B12 shots helped?

[Sleepybunny]

B12 deficiency can cause mental health problems. The PAS (Pernicious Anaemia Society) website has lots of useful info.

pernicious-anaemia-society....

This site is useful too.

b12deficiency.info/

[Gambit62 Administrator]

I had 4 decades of depression. Was diagnosed as having low B12 incidentally in December 2012 ... and was another 15 months before I gave up on the NHS and started treating myself as I just wasn't getting any better on the normal regime. I really hadn't expected that getting the doses I needed would make the depression so it was a bit of a surprise when a few months into treating myself the depression went away.

I actually use a nasal spray as my main means of delivery rather than shots but occasionally do sub-cutaneous injections.

It is possible that the shots might be enough to 'cure' depression as the doses I need are really high - I think I probably have an autoimmune response to B12 and the only way to beat it is to keep the levels high ... and if I didn't have that response then may be the normal regime would have been enough.

By the time I started treating myself my neuropsychiatric symptoms had progressed beyond depression into acute anxiety and mild psychosis.

However, your situation does sound rather complex as there are a lot of overlap between B12 and other conditions and unfortunately it could also be two or more things interacting together.