Emisphere - First Oral Prescription B12 Tablet

[snakely]

This came up on my google alerts today. Seems interesting, albeit cyano-based.

multivu.com/players/English...

[Poppet11]

I got about 2 seconds into reading it. It says it 'normalises b12 levels' - they would be the same b12 levels that should be ignored once treatment commences because they are not reflective of how effective the treatment is, would they?

If somebody else manages to read it all and it says they tested it on humans with symptoms and it worked over a consistent period of time, please let me know...

[Secondchance in reply to Poppet11]

It mentions actively transporting B12 as opposed to relying completely on passive diffusion which is good but only doubles absorption in normal non-B12 deficient people so may be even less in those who are deficient. I would want to see large trials addressing symptoms as well as levels before trying myself.

[engels]

Success measured by normalisation of blood serum level? Snake oil.

[Poppet11 in reply to engels]

Wondered how long it would take before you posted!

Worrying though - if it's going through on prescription doctors will cling to it like a drowning man.

[engels in reply to Poppet11]

I'm obviously too predictable.

[Poppet11 in reply to engels]

You and me both, mate.

[Hidden]

Hi,

It was discussed on the old PAS forum in 2008, its not that new..some more info:

This is the company:

emisphere.com/eligen.html

emisphere.com/oral_vitamin_...

files.shareholder.com/downl...

It may well be good news for some, but its very money orientated as in it cost this much for an injection and only that much for a tablet..

[Poppet11 in reply to Hidden]

The tablet thing appeals to doctors due to injections taking up nurses' time though, Marre.

They will do this tablet thing eventually - because it's what the medical profession want to hear.

I just wish they'd test these things on people. I know what happened to me - my reaction at first to the tablets was spectacular, but after you get B12 into your cells the absorption in the intestine changes and passive diffusion doesn't take place in the same way. They become virtually useless.

The same tablets on me, which had been so spectacular at the start - had zero effect three years later.

I do wish they would do long term studies on people before they started licensing stuff.

[Chancery]

Unfortunately this is a promotional piece from the company that makes it. That's a bit like asking Walmart to extol their own wage policies - they're not going to criticise it, are they? Or paint a true and balanced picture.

I'm afraid until an impartial third party examined it it's not worth the ether it's printed on.

[Secondchance]

It mentions actively transporting B12 as opposed to relying completely on passive diffusion which is good but only doubles absorption in normal non-B12 deficient people so may be even less in those who are deficient. I would want to see large trials addressing symptoms as well as levels before trying myself.