Risk factor for Alzheimer’s disease breaks the blood–brain barrier. APOE4.
People who carry the gene variant APOE4 are at higher-than-average risk of developing Alzheimer’s disease. It emerges that this variant is linked to defects in the blood–brain barrier and subsequent cognitive decline.
Nasty!! Don't let's allow the insurance carriers or fiances to find out.
It's a risk factor only, without exposure to xenobiotics it is benign. Genes are our tendancy and not our destiny. This is a modifiable risk. It trips my trigger when research is patient blaming.
The risk is "modifiable" how?
I have two copies of this genetic variant. I'm pretty sure the potential stress caused by knowing I have this and worrying about possible outcomes is worse than their simple existence, since I'm already doing all the recommended things to take care of myself. I'm going to forward this to my MDS and then try not to think about it!
Good plan it’s only statistics😊
❤️
"Good plan?" So you know it's changed by stress? Me, I always feel better after worrying.
We might not disagree! When you say you feel better after worrying, it sounds like you worried and then you stopped. That's what I did, too -- after learning about it and taking some steps that felt productive. What I meant is that I don't want to dwell in fear. In my own experience, chronic stress does lead to poor health (not to mention happiness) outcomes.
Other APOE4 news that is relevant and which I'll be researching:
Vascular Dysfunction in the Brain as an Initiating Event in Parkinson’s Disease40 Hz Light Flicker Alters Human Brain Electroencephalography Microstates and Complexity Implicated in Brain Diseases 2021
long-term Lithium use tied to higher risk of VTE, Parkinson and kidney diseases
AUTOPHAGY helps defeat BRAIN disease, says Dr Nadir Ali, M.D.
Achieving brain clearance and preventing neurodegenerative diseases—A glymphatic perspective
