40 Hz Light Flicker Alters Human Brain Electroencephalography Microstates and Complexity Implicated in Brain Diseases frontiersin.org/articles/10...
"Previous studies showed that entrainment of light flicker at low gamma frequencies provided neuroprotection in mouse models of Alzheimer’s disease (AD) and stroke. The current study was set to explore the feasibility of using 40 Hz light flicker for human brain stimulation for future development as a tool for brain disease treatment. The effect of 40 Hz low gamma frequency light on a cohort of healthy human brains was examined using 64 channel electroencephalography (EEG), followed by microstate analyses. A random frequency light flicker was used as a negative control treatment. Light flicker at 40 Hz significantly increased the corresponding band power in the O1, Oz, and O3 electrodes covering the occipital areas of both sides of the brain, indicating potent entrainment with 40 Hz light flicker in the visual cortex area. Importantly, the 40 Hz light flicker significantly altered microstate coverage, transition duration, and the Lempel-Ziv complexity (LZC) compared to the rest state. Microstate metrics are known to change in the brains of Alzheimer’s disease, schizophrenia, and stroke patients. The current study laid the foundation for the future development of 40 Hz light flicker as therapeutics for brain diseases."
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Bolt_Upright
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Thank you, interesting information. HWP has been using the coronet helmet from AU nonsignificant improvement to report, only using once a day for about a month. I don't look at the light as it bother my eyes, seems to work differently than what you are describing because does not impacting visual field. I have also seen light helmets with a probe to clip to nose to pulse the light through nasal cavity. Those are very $$.
I have a MindPlace Brand Limina Light And Sound machines that comes with a 40 htz program. You can just listen to the beat or wear the light goggles that come with the machine. These machines have been out for many years and I first got one to assist with Meditation many years ago. The only warning is that if you migranes it is contraindicated for you. The brightness of the light and sound is adjustable.
Thank you Bolt for this post I have now been using the red light coronet for 3 months, twice a day. It works at 40 Hz as in the article.
It is hard to describe its effects but the best way I can put it is that it stimulates my brain to the point that I can feel it being physically active (I hope I don’t come across as totally crazy but it is almost as if I could ‘hear’ my brain being active).
I do a lot of things to slow down progression and it is difficult to attribute specific benefits to anything in particular but I am definitely not planning on stopping using my coronet.
In this video about another light therapy helmet being tested, he mentions that focusing on the back of the head, closer to the hippocampus , is best for PD. I have tilted my helmet back off my forehead to emphasize the back of my head. I’m not sure if that is advisable but maybe it’s getting more light to where is ideally should be. Obviously I need to improve my knowledge because I thought the basal ganglia was the focus of PD.
I have been using the welred coronet twice a day for 2 months. It has significantly improved my jerks which occurred daily. I am now going to stop using it to see if the jerks come back.
"The visual stimulation equipment consisted of two modules, a programmed tunable frequency signal generator and a LED lighting unit. The LED lighting unit consisted of six LED strips evenly fitted on a 30 cm × 20 cm plane board. Each LED strip was 50 cm long (12 V) fitted with 18 individual LED light bulbs. The specific frequency of light flickers was generated using the signal generator. The driving signal (0–5 V square wave, 0.1–120 Hz, even distribution) was generated by an Arduino UNO and amplified by a pulse-width modulation signal amplifier. The input voltage signal for LED strips alternated between 12 and 0 V, and the corresponding luminance switched between maximum LED luminance and complete dark. Dynamic luminance curve was verified using photosensitive diodes and oscilloscope, confirming a stable frequency and square wave-shaped illuminance. Two types of flicker signals, i.e., 40 Hz and random frequency, were produced as described previously (Zheng et al., 2020). The 40 Hz signal has a consecutive 2.5 ms cycle. A random flicker luminance was produced as lights were on and off for a randomized interval > 0 that averaged 12.5 ms. For example, random stimulation with off intervals was ranged from 0.2 to 34.1 ms. Therefore, the frequency of light flickering was random. The luminance switches between maximum LED luminance and complete dark. Eyes-opened, 30 s of resting-state EEG was collected from all subjects. The same test was also performed on subjects with one side-eye covered to allow only one eye exposure to light flicker.
All subjects sat at a comfortable chair and looked at a fixation point on a computer screen 40 cm away, which continuously displayed light flickers at the specified frequencies for 30 s. The participant was allowed to rest for 30 s and followed by another 30 s of light flicker while the EEG was collected."
Wouldn't this be counterproductive in PD? It will enhance the Brain's cleaning process including plaques and dead neurons, and new neurons are not being made, so.....
I just hi-lighted your phrase and Googled: Activation of autophagy ameliorates age-related neurogenesis decline and neurodysfunction in adult mice assets.researchsquare.com/f... 6-531e-4a13-bed5-45f92dc300cb.pdf?c=1647529872 "In summary, our results revealed that autophagy was closely correlated with adult neurogenesis. Genetic suppression of Atg7 compromised neurogenesis; conversely, pharmacological activation of autophagy enhanced middle-aged neurogenesis and restored middle-aged brain function.Apr 8, 2021"
I have fallen off my low carb diet the last week. I've even been eating glutens. Time to get back on the horse. I need to try at least a 24 hour fast this weekend.
I fell off the horse for a bit. At first I felt fine which wasn’t good bc then it made getting back on the darn horse harder but wow, when it hit it hit. Bloated , brain foggy grumpy mess! Back on the horse! I love a 24 hour fast. I think my brain needs it.
Yes! For the first 3 days I was like "hey, I guess I did not need this diet", then yesterday things started going south and today was awful. Tomorrow the sun will be out and it will be a new beginning.
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Photomodulation - which device would you choose?
Fasting. I recently have gone to OMAD.
GREAT NEWS! Intra-Nasal FGF-1 Human Trials have started! WATCH video! Tremor reduced!
