Hi all. I have been taking 2 X soluble solpadol 30mg/500mg, four times a day. For about two months now. I have started feeling very nauseous in the early morning and it only eases off around midday. I have a feeling it is the solpadol. Anyone know if long term use of this medication causes this? I have been trying to cut down but then have to rest a lot during the day. Too much pain otherwise.