ca-125 after debulking surgery

[nordic5]

Could You answer, Ladies, how high (or mayby low) was Your ca-125 level just after surgery and before chemo. And was it problem for oncologist?

[SuffolkJen]

Hi nordic5

My CA125 was 8 after surgery and before chemo. It was 76 before surgery xx Jen

[nordic5 in reply to SuffolkJen]

Thank You SuffolkJen, so it was really R0 surgery

[SuffolkJen in reply to nordic5]

It was, but at the time it was thought to be a fibroid & not OC. Pathology showed clear cell OC so a big shock xx Jen

[Jazmin222]

Mine was 69 when clear cell cancer was diagnosed and post surgery it dropped in the following months, 18, 16, ending at 7 (5 months later) I thought this was the success of the chemo but they told me it was actually what they expected to see post-surgery … with the slightly higher numbers being due to inflammation.

[nordic5]

Hi Jazmin222, my ca-125 was ten times lower after surgery then before, but still not normal, During chemo successfully dropped 10 and is the same next 18 months

[Jennifer1959]

Hello - Before surgery it was 111 and then dropped after surgery to 5. something and has stayed 5. something throughout chemo. Fingers crossed it stays that way! Was diagnosed with Mucinous Inflitrative OC 1C. x

[SopSinger]

CA125 levels vary enormously even for individual patients, and the level can be elevated by many things other than cancer (false positive). It can also give false negatives. The number itself is almost meaningless. The trend is much more informative. Don't concentrate on the number, it'll just cause you stress.

[Saintgermain]

My CA125 was 4300 before debulking as inflammation can cause it to elevate which a debulking surgery can do it my CA125 wasn't drawn until I was midway thru carbo/taxol at that time it was 15 at end of frontline it was 6.

[nordic5 in reply to Saintgermain]

Me the same, normal range after op and 3 chemo cycles. Of course I was hope to have it just after debulking to feel "clean of disease".

[Pawpaw22]

Before was 180. After was 19. Very reassuring.

[Marieck]

so mine was clear cell and it was only ca 125 of 28 before surgery and now it’s around 7. However seems for me the ca 125 is not a great marker

[Saintgermain in reply to Marieck]

Mine is Endometroid don't know if its my type but the CA125 is a very good marker for me

[nordic5 in reply to Saintgermain]

ca-125 is actually strange marker, for me is good, but Im not sure it depends on histology type (HGOC in my case); important is the initial level, like with another cancers (CEA eg)

[Dinahhaynes]

I had CA-125 of 10180 pre surgery then 209 3 days after. Now 6 👏🏻👏🏻👏🏻

It had spread from ovary to bowel, spleen omentum and more. Lots removed and 19.5 hrs surgery but that saved my life. Now on maintenance chemo to hold back return of BRCA cancer. Good luck all. Keep smiling 😊

[nordic5 in reply to Dinahhaynes]

👍