First recurrence, which coctail to choose?

[Beatyourself]

Dear Ladies,

My worst nightmare came true. I had some indications on CT scan already in January, that something is cooking. In June CA125 was increased to 100 and another scan was done that confirmed more activity incl some new ascites in abdomen and 1,5 cm hyperdensity in liver. We were then a month before hols, my doctor said till I have symptoms we do nothing just switched me from Niraparib to tamoxifen and figured we wait and see for symptoms. I went back to him 3 times past month to ask if it was good idea to fly to US (from Netherlands) as I was scared something is going to happen. He told me to go, enjoy, send postcard, it could be 6 months nothing gonna happen. and after all we go to US, so what I am worried about. … Moment we landed I figured my belly is bloated. 3 day later I ended in hospital that confirmed large ascites so we flew back home and I got 6 liters drained on Wednesday. Called with oncologist today and he says we need to go to chemo and I can choose from 3 options (not sure yet which). One of them is chemo I had last year when diagnosed carbo/taxol - but wonder if it makes sense if it recurred so quick?

History: Diagnosed jan 2023, HGOC 4B, 3xchemo, debulking,3x chemo, august 2023 started with Niraparib as I was BRCA negative. Switched to tamoxifen in June after Niraparib didnt work apparently. I am 42.

Fun fact 1: I suffered from 20 hot flushes a days since debulking surgery last April. And since my belly got bloated again they are completely gone, I didnt sweat a drop either. Anyone experienced anything similar?

Fun Fact 2: I am getting married end of august …. We waited for year so I have hair and all this time I was scared I will recur before that. So I i did. Sorry for long post, I guess is one way of digesting this nightmare Much hugs and love to all of you and thank you for reading me.

[Pixiepurple]

Hi Beatyourself,

I am so sorry to hear you are going through this awful journey. Similar to yourself, diagnosed June 23 6 rounds chemo then debulking 6 weeks later started Avastin & May 24 1st recurrence in 2 lymph nodes. I'm on Carbo/gem, and awaiting results of CT scan. So hopefully will see a reduction.

Thinking about your wedding I haven't lost my hair but its gone a bit thinner. Focus on whats ahead your very special day. Congrats xx

[Beatyourself in reply to Pixiepurple]

Thank you Pixiepurple ♥️ warm hugs to you too for having to go though this journey

May I ask you how often you do you get chemo and whether you have other side effects ? I pray for great results for you ❤️

Very sweet from you, my wedding is in Budapest so is not just about the hair but whether I will be in condition to do it, travel and so but guess next days will tell 😢

[Pixiepurple in reply to Beatyourself]

Hi Beatyourself,

Day 1 carbo/gem

Day 8 just gem

Day 21 carbo/gem

The days I have both it takes me about 5 days to get over the tiredness. The week I only have gem no affects. I went overseas a month after I started treatment n was tired for about 2 days then I was grand.

Best of luck with your wedding plans. I really think you will be good xx

[Beatyourself in reply to Pixiepurple]

Thank you for sharing Pixiepurple, it gives now lot of hope and some peace.

Much love and best wishes to you 😘

[Schnauzer19]

So sorry you are going through this, life can be so unfair. I really hope you are well enough to get married. Please let us know how you get on. Sending love and hugs back x

[Beatyourself]

thank you dear 😘 best wishes to you ❤️