Normal CA-125

[Starflower2946]

I am going in for a total hysterectomy on the 25th

They suspect a Granulosa Cell Tumour due the presence of a mass on my ovary and thickened womb lining

However my CA-125 is in the ‘normal’ range, I am just curious if others received a DX with normal CA-125?

I am ready for whatever comes but just curious as I always see elevated CA-125 in those with a dx of OC.

I hope it’s ok to ask this question

[wendydee]

I was told, by the lead consultant at our local hospital’s gynaecology oncology dept, that the CA125 is not always accurate. It can be absent as a marker or give falsely raised levels sometimes. It’s sounds as if your medical team are covering all the possibilities. I hope you’ll be ok after your op. It sounds as if your medical team are looking after you well.

All the best,

Wendy xx

[Starflower2946 in reply to wendydee]

Thank you

I was wondering if they were being a bit reactive as it feels quite extreme when we don’t know what it is yet!

But your msg was helpful

Good luck ❤️

[Starbarn]

hi starflower . Unfortunately not all cancers are shown up by raised ca125. I have clear cell and that is one of them.

Good luck with your operation.

[Starflower2946 in reply to Starbarn]

Thank you for this

Helps to make sense of their plan

Hope all works out for you ❤️

[Leniko]

my CA125 was always very telling and accurate, but I know some women’s are not. You’ll have to look at trends if it’s decided you must go down this road.

[JMB1966]

Hi Starflower

My CA125 was 28 at diagnosis so within normal range but following radical surgery and six rounds of chemo it dropped to 7 and now hovers around 10-12.

I had an endometrioid carcinoma of the left ovary and was stage 1C, so one of the lucky ones to be diagnosed early.

Very best of luck next week

Janine

[Starflower2946 in reply to JMB1966]

Thank you ❤️

[cavebaby]

hi,

I was diagnosed last year with stage 1a GCT and my CA-125 was normal throughout. It is not a good marker for GCT. Inhibin an and b are more indicative. Good luck with the surgery and happy to chat after. If it is GCT there are UK (and Ireland) and worldwide Facebook groups specifically for GCT, as it is one of the rarer Ovarian Cancers the usual management does not really apply. Its groups are UK GCT survivor sisters! and GCT survivor sisters! Xx