ICON8 Trial

[ZenaJ]

Hello lovely ladies,

I have had the results of the ICON8 trial today. I thought I'd already heard them and let you all know but for those that don't know anything about it, it was a trial to see if giving carboplatin every three weeks and paclitaxel once a week for a total of eighteen weeks would be better than giving both every three weeks. It turned out that it didn't make any difference either way so three weekly chemo will still be the norm for everyone.

This trial is now completed and shows it made no difference in preventing cancer returning or to improve how long women with ovarian cancer lived.

I hope everyone is keeping a well as possible and wish everyone well.

[Lyndy2]

Thanks ZenaJ I don’t remember reading this before but good to know I guess xx

[Sashay2020]

Thanks for the update, Zena.

Best wishes,

Sashay

[MH500]

good to know, thanks Zena xx

[Shan67]

Thank you Zena 💕

[Caleda4]

Thank you Zena, very interesting for future reference.x

[Boot1947]

Thanks, Zena. Good to know. I was on ICON8 eight years ago on the weekly arm and psychologically it suited me and my routine to know I was having chemo every week (except when my bloods were rubbish!), rather than every three weeks. I ended up having only 13 sessions, rather than 18, but I have been NED ever since (touch wood!), despite being 3a. Deb x

[ZenaJ in reply to Boot1947]

We're very lucky. I had to have a few blood transfusions too and it was like having new batteries. I was diagnosed stage 3C in 2013 so been really lucky. xx

[Riverflo]

Thanks for sharing Zena. Always good to hear about trials. X

[Newbery3]

Thanks for going through the trial for us all xxx

[ZenaJ in reply to Newbery3]

Before getting cancer I used to do paid trials so I felt it was no bother doing this one. It was just a shame that it didn't make any difference at the end of the day but you have to try these things to find out. I'm still on a genetic trial where I send my blood to the hospital every year and boy does that come round quickly. I'll never find out the results of this one though. xx

[Catfeeder]

Thankyou x

[Frenchhouse3]

Thanks for sharing Zena, I didn’t even know about this trial, so it’s interesting to read. Xxxxx

[ZenaJ in reply to Frenchhouse3]

I've been on it for about 10 years but it's all over now and although the chemo was weekly for 18 weeks, I didn't find it too bad. Then again, I didn't have anything to compare it with.xxx

[Seedlings]

Hi Zena,Thanks for this information. I was on this trial when first diagnosed in July 2018. I was on the weekly arm . It was tough going as I found I was just picking up 4/5days post chemo ,when I was back in again for next dose. I had my first recurrence in December 2020 and had the same treatment schedule.

Unfortunately I am back on treatment again , just two weeks but am getting it once every three weeks. The difference is incredible. Yes , very tough for a week but now feeling very well and "normal".

I am hoping to get into remission again , here's hoping!!.

Tks again Zena.

Ann

[ZenaJ in reply to Seedlings]

Hi Ann, it's so disappointing when recurrence happens so I do hope all goes well this time. I started the trial in 2013 and they've finished with it now, so my letter said anyway.

All the best for a brighter future. Zena x

[delia2]

Thanks, Zena. It’s wonderful how well you’ve done.

[ZenaJ in reply to delia2]

Thanks Delia, I've been much luckily than most. I hope you are doing well. xx

[KimLJ]

Thanks for that. I was wondering as I was on that trial and had Pacitaxol weekly. I was 3c and 4 years NED xx

[ZenaJ in reply to KimLJ]

I was 3C and 10 years NED in February. We've been very lucky.

[Goodgirl98 in reply to ZenaJ]

hi Zena, I have a question. Do you participate in trials when you are NED as well or did these start earlier when under treatment?

[ZenaJ in reply to Goodgirl98]

Hi, these trials started when I was on treatment. I was asked before I started, as soon as I was diagnosed, and didn't hesitate to help. One trial is still ongoing. xx

[Goodgirl98 in reply to ZenaJ]

wow, you are so brave and amazing!

[Pianoplayer731021]

Thanks for checking this out ZenaJ. Sending best wishes, Donna

[ZenaJ in reply to Pianoplayer731021]

Thanks Donna, we don't always get the results of trials so it was nice that they got back. Hope you are okay. xx

[Hidden]

Thank you for informing us. Those things are good to know.