Moms chemo today

[Inguc_is]

My mom has chemo today her second recurrence after 5 month from last chemo, she het palitaxel with platin same as first time 2017 and 2021 . I thought it will be non platinum but they said as she has very good results they try again, is there anyone who was in same situation do platin works? Finger crosss!!!

[fendweller]

Hop your mum does well on Carboplatin and paclitaxol . I had this first line and after six cycles and surgery was told there was no evidence of disease , I had a recurance after nine months ,I had six more cycles of carbo and paclitaxol, it reduced the disease and I had a break , when the disease started to progress again I had six more cycles of Carboplatin and paclitaxol, again it reduced the disease , I them had a parp , Rubraca, sadly didn't work for me and I've just finished six cycles of carbo and caeleyx ,it's reduced the disease ,I'm now on a break. There are lots of options left for your mum ,we all respond differently to this disease and treatment so no one can say this will work or that won't work ,trust your team but always question. Wishing you and your mum well .Cheryl.

[Inguc_is in reply to fendweller]

I hope it will work for my mom again also 🙏🏼🙏🏼🙏🏼

[fendweller in reply to Inguc_is]

Xxx

[SUE7777]

Platinum chemo works the best and if your Mum is responding to it then that's great. They will keep an eye on her. Sue

[Inguc_is in reply to SUE7777]

She was responding good but it came back fast :(( but they choose to try one more time

[SUE7777 in reply to Inguc_is]

🤞🤞🤞🤞 has your Mum had a parp, if she is platinum sensitive then there is a chance it would work for maintenance

[Inguc_is in reply to SUE7777]

She made brca test dont know result yet there is only olaparib for brca positiv which they offer

[SUE7777 in reply to Inguc_is]

She should be able to get a parp without being BRCA talk to the oncologist, it might mean a Clinical Trial. She could be HRD positive.

[Inguc_is in reply to SUE7777]

Just get BRCa results - negativ what is HRD?

[SUE7777 in reply to Inguc_is]

HRD is another DNA test it's when your DNA is unable to repair itself

[Inguc_is in reply to SUE7777]

It can be done with blood?

[SUE7777 in reply to Inguc_is]

yes, I would expect it to be done at the same time as BRCA

[OvacomeSupport Partner My Ovacome Team in reply to Inguc_is]

Hi there Inguc_is

Thank you for your question about HRD. I can see you’ve already had a response to your query, but just wanted to share some more information that I hope may be helpful.

BRCA1 and BRCA2 gene changes are both types of HRD (homologous recombination deficiency) but some people who are BRCA negative, are positive for other types of HRD. HRD describes a process when the body is unable to repair damaged pathways and cells are unable to fix broken DNA, meaning cancer cells also have a harder time repairing themselves. Presently, HRD status mainly has relevance when considering eligibility for PARP inhibitors. HRD testing is a fairly recent development for those who are newly diagnosed. Access to retrospective testing can be challenging as the test requires a large tissue sample which may not be easily available, so this may be a topic for your Mom to discuss with her clinical team.

Ovacome recently hosted a webinar with Dr Rowan Miller about HRD that you may find of interest: youtube.com/watch?v=dcNRNU6...(Not working as expected?)

In addition, I wanted to let you know about our monthly online friends and family group that you would be really welcome to attend. This is a friendly and supportive environment for anyone caring for someone with an ovarian cancer diagnosis to meet others in similar circumstances, ask questions and share experiences. For more information, please visit: ovacome.org.uk/event/family...

Please don’t hesitate to get in touch if you have any questions or would like to talk things through. You can contact us on this forum, by calling our support line on ([phone]/ ([phone] or by emailing [e-mail]. We’re here Monday – Friday, 10am – 5pm (U.K time).

Best wishes

Annie - Ovacome support