Anyone help ca125 raised twice was it something simple. I’m so worried

[Selena47]

Anyone have a raise ca125 twice and was for something else other than cancer. Had a reading of 56 had ultrasound shown nothing. Then went to gynaecologist had tv ultrasound was clear but showed pcos. She repeated the blood test that day. She didn’t seem to concern about it, got phone call for a booking for ct scan. Didn’t know why. Rang gp. She said he’s just being cautious. That your blood went up to 67. She said that lots of things can raise it. I had pain on and of since having my son 2 years ago. Had a very bad birth with a 4th degree tear. Plus damage to back passage. I think I have ibs also. Just wondering did anyone have something similar and turn out to be something simple. My mind in over drive. I’m so worried. I’m a single mother. So scared at what this ct scan could show.

[Lyndy]

Hi Selena47 The ca125 can be affected by any inflammation or infection. It’s also not a foolproof way of diagnosing Ovarian cancer. But when it is raised, the first thing a doctor wants to do is rule out OC as a cause. Try not to worry if you can (I know it’s hard). Many of us have campaigned for early diagnosis and prompt testing because we know that the earlier it’s caught the better but this does mean that more women like you go through the ‘is it, isn’t it’ stage as you are doing now. With any luck it will be nothing to do with cancer. xx

[Selena47 in reply to Lyndy]

Thank you

[Elena_Ukr in reply to Selena47]

Hi Selena, it’s quite possible IBS, but anyway you should have CT scan to rule out OC. Do not go crazy ahead of time. Try to not think about it using everything that works for you - books, music, movies, friends- stress is not good for us itself. Background: Cancer antigen 125 (CA-125) is a tumor marker used for the diagnosis and monitoring of ovarian carcinoma. It can also be elevated in endometriosis, inflammations, and in nongynecological malignancies. Up to date, serum CA-125 levels in inflammatory bowel diseases (IBD) have not been studied before.

Aim: To assess the levels of CA-125 in patients with ulcerative colitis (UC) and Crohn's disease (CD).

Methods: Serum levels of CA-125 were investigated in 68 cases with UC (male/female: 47/21), 32 CD (male/female: 21/11), and 31 healthy controls (male/female: 16/15). Levels of CA-125 were also compared among UC patients according to lesion location, severity, and activity of CD.

Results: Serum CA-125 levels were 17.29+/-24.50 U/ml, 15.56+/-20.74 U/ml, and 8.85+/-2.62 U/ml in patients with UC, CD, and healthy controls, respectively. Serum CA-125 levels were significantly higher in UC compared to control group (P=0.001). Serum CA-125 levels were higher in CD patients compared to control group but there was no significance (P=0.087). Serum CA-125 levels were higher in pancolitis compared to distal type and left-sided UC.

Conclusions: Our data suggest that serum CA-125 levels may be increased in patients with IBDs.

[Selena47 in reply to Elena_Ukr]

Thank you. Trying to distract myself and not stress about it. Until I know there’s actually something to worry about.