PARP

[Harp-1]

Anyone got PARP? Is it effective? How long need to be taken for an ovarian cancer stage 3 and how expensive?

[Katmal-UK]

Hi. I have been on Olaparib since beginning of Jan 2014 on a trial which has come to an end but I now continue on the drug. I dont pay for it but understand its in the region of £60k per year. I have heard some ladies have self funded for a year then are able to access the drug on compassionate grounds from the manufacturer though have no details as to how to access that. I think its best if you speak to you oncologist regarding accessing a parp. Best Wishes, Kathy xx

[Lizzieanne in reply to Katmal-UK]

Can we get this free on NHS. Read a few positive posts on this drug and I may have to go on an inhibitor so very interested in the good results this one seems to have

[Katmal-UK in reply to Lizzieanne]

Hi, yes I believe its been approved by NICE as a maintenance drug but im not sure of the criteria for being given it. Prob best course is to contact your Onc or Macmillan or the Ovacome team to see if they know the criteria. xx Best wishes xx Kathy xx

[Lizzieanne in reply to Katmal-UK]

Will do. Thank you

[Newbie_2020]

Here are the NHS criteria for prescribing Olaparib

uhs.nhs.uk/Media/SUHTExtran...

Most criteria are also applicable for Niraparib but it is prescribed for those who have tested negative on the BRCA genetic test.

[Lizzieanne in reply to Newbie_2020]

Thank you v much

[Hidden]

I’ve been on Olaparib for 18 months. I’m BRCA 1.

I live in Ireland. We have a drugs scheme. I pay €124 per month for all my drugs. I know the real cost of them is thousands per month but I don’t know the exact cost.

Anne 🤗

[Lizzieanne in reply to Hidden]

Gosh that's interesting and a great idea. Thank you

[delia2]

I’ve been on Olaparib for five months. I’m in Massachusetts. I know it would cost about 16000 dollars a month here but the manufacturer, AstraZeneca, has a generous way to help fund those without insurance. In the UK you may need to be BRCA + to go on it but you could get Niraparib. Not sure about Rucaparib which seems to be getting more popular.

[Lizzieanne in reply to delia2]

Thank you

[win_56 in reply to delia2]

Hi I am going on Rucaparib after first recurrence. I'm platinum sensitive and have had a good response to chemo. My oncologist said at guest I would be in Niraparib but because of the covud situation she has changed to Rucaparib because it's lesser side affects and not so hard on the bloods and apparently less hospital visits for blood work. She said the efficacy is just as good as Niraparib and I clarified this with the ovacome team.

[Lizzieanne]

Thank you

[Harp-1]

Thanks everyone,

[Pianoplayer731021]

I took Zejula for 2 months at 200 mgs. daily. I am BRCA negative. My hemoglobin dropped so low that I had a blood transfusion. I’m off from Zejula for a week and then more blood tests. Don’t know what the doc will do next.