New Clinical trial : News | headlines Clinical... - My Ovacome

My Ovacome

17,619 members19,897 posts

New Clinical trial

DanL2017 profile image
1 Reply

News

| headlines

Clinical trial tests customized treatment for ovarian cancer and peritoneal mesothelioma

Email

Twitter

LinkedIn

Google+

Share on Facebook

Share on Pinterest

Ovarian cancer

Ovarian tumor microenvironment

Photo courtesy of NCI Visuals Online

Patients with advanced ovarian cancer or peritoneal mesothelioma may be eligible to participate in a new clinical trial at the NIH Clinical Center.

Christina Annunziata, M.D., Ph.D., of the Women’s Malignancies Branch is leading the Center for Cancer Research’s participation in a study of an experimental, customized therapy for advanced ovarian cancer and peritoneal mesothelioma that have not responded to standard treatments. Ovarian cancer includes cancer of the ovaries, fallopian tubes or abdominal lining (peritoneum). Peritoneal mesothelioma is a type of cancer that affects the peritoneum and is caused by ingesting asbestos fibers. MCY-M11 is a drug derived from the patient’s own white blood cells, which are separated out from the patient’s blood and sent to a manufacturing facility. There, the collected white blood cells (mainly T cells) will be injected with genetic material. This will create a new protein on the T cells that may allow them to target specific kinds of tumor cells. When a sufficient number of genetically altered cells have been produced to make MCY-M11, the customized drug will be sent back to infuse the cells back into the patient’s body. The entire process will take 3 to 4 weeks. The study is designed to find the highest safe dose of MCY-M11.

Clinicaltrials.gov identifier: NCT03608618

NCI Protocol ID: NCI-18-C-0143

Official Title: A Phase 1 Study of Intraperitoneal MCY-M11 Therapy for Women With Platinum Resistant High Grade Serous Adenocarcinoma of the Ovary, Primary Peritoneum, or Fallopian Tube, or Subjects With Peritoneal Mesothelioma With Recurrence After Prior Chemotherapy

The Center for Cancer Research is NCI’s internal cancer center, a publicly funded organization working to improve the lives of cancer patients by solving important, challenging and neglected problems in cancer research and patient care. Highly trained physician-scientists develop and carry out clinical trials to create the medicines of tomorrow treating patients at the world’s largest dedicated research hospital on the campus of the National Institutes of Health in Bethesda, Maryland.

For more information on CCR clinical trials click here, and subscribe to have the latest CCR clinical trials sent directly to your inbox.

NIH…Turning Discovery Into Health®

U.S. Department of Health and Human Services | National Institutes of Health | National Cancer Institute | USA.gov

Written by
DanL2017 profile image
DanL2017
To view profiles and participate in discussions please or .
Read more about...
1 Reply
Neona profile image
Neona

Looks as though it is not for clear cell again.

You may also like...

Requests to Join Clinical Trials

leading-edge clinical trials that aren't available in their local health service. Cancer Research...

Anyone on a clinical trial?

No Clinical Trial available for me

letter from The Marsden to say there is not a clinical trial I can try at the moment. With no...

Waiting for Appointment for Clinical Trial

available to me other than to be considered for a clinical trial, which of course I’m keen to try....

Clinical trial? Niraparib?

hour drive to cancer centre where she would have to do clinical trial. Her local cancer unit for...