Rotterdam protocol

[Agility]

Hi anyone been on this and able to describe how tough it is. I faired well during taxol/carboplatin. I’ve been warned I won’t in Rotterdam regimen of etoposide and cisplatin.

[Hidden]

Hi there this is one I haven't done. It may not be as bad as you think. Wishing you all the best

[Agility in reply to Hidden]

Thank you

[angeladale]

Ah , I have been on Rotterdam regime ....January 2013..for eight months ....having been treated with carbo taxol , and gem carbo in 2011 to 2012....I was told how hard it was , but rather sailed through it all . I lost my hair again, but the bugger was kept at bay until the following January . My recurring friend is pretty regular , but I am still here ! Cisplatin needs a long time because of kidney flushes , and etoposide you take daily as a tablet ( although I believe the Christie does it differently ) ...sickness pills essential , and therefore laxatives too ....but I am sure you can get a routine going ....I had cisplatin a second time in 2015 , and recently finished a trial , now on cyclophosamide . Where there's a will .....Every best wish xAngela Dale

[Agility in reply to angeladale]

Thank you. You are in resilient lady. She who dares wins. Can you explain the kidney flush thing. It’s just that they said, they might need a couple of days to support by kidney before I start the chemo.

Also I see you also did the promab trial. I’ve just been told to get histology done to see if I have high micro satellite instability (HMSI) which would qualify me for it.

So we seem to be on very similar paths....really appreciate your reply.

Jane

[angeladale]

Cisplatin is hard on the kidneys in that the kidneys work hard to get rid of it . as I undertand it ....dont quote me !

The flush is through the port / cannula , about an hour dripped in and you get to pee a lot ! Yeh ! Sit by the loo in the ward !

Then in goes the cispaltin ....hair loss , exhaustion , but if you can go with the flow all the better . The etoposide ( probably ) didn't do it for me , but cisplatin did , which is why I had it a second time . Keep your liquid intake high nevertheless .

I am now getting a bit weary with it all ....but when the weather picks up we will all feel better I am sure .

Good Luck with it all x

[Agility]

Thank you. I have a kidney under pressure which is why I was interested in the kidney flush comment. It explains why they went from outpatient day 1 admin plan to inpatient day or two kidney prep before chemo. Well I shall see what next week brings. Thank you again for sharing x

[Alikay]

I'm currently on this regime, having day 1 of 2nd cycle at the moment. Apart from feeling very tired and having treatment deferredby a week due to low white cells, I haven't found it too bad. I hope you are able to tolerate it and does the job in kicking the beastie into touch. Take care. Ali xx

[Agility in reply to Alikay]

Ali good luck. I hope you continue to tolerate it well enough when your bloods allow. Are u low grade?

[Rlenesue]

I have had cisplatin too. They put a port in my belly so they can do belly washes. I hated every minute of it but the chemo did get rid of the cancer