tymlos

[Screwed]

can one relay off Prolia with tymlos? Any negative or positive side effects?

[bellybuddie]

I read to stop prolia, it is best to use Reclast. This is due to the large quantity of immature osteoclasts (suppressed during prolia treatment) become mature, hence increasing bone resorption. Every patient is different, so it is best to ask and work with an experienced doctor who is familiar with prolia cessation.

[uncountable3]

Going directly from Prolia to Tymlos is not advised. You need something to cut the resorption spike that occurs when terminating Prolia. Tymlos does not reduce resorption at all . It actually increases resorption. Usually a bisphosphonate is used. Evinity might work as it has both anabolic and anti-resorption qualities.

[Anonimoveneziano in reply to uncountable3]

Relaying off from Denusumab it is usually advised Zolandronade infusions with regular bone biomarkers tests, CTX and P1NP evwry 3 months. There is a group on FB with very usuful information backed by white papers from medical research studies.

Prolia support group on FB

[Screwed in reply to Anonimoveneziano]

Unfortunately, I do not have FACEBOOK.

[MayGodBlessYou]

my Mum was recommended evenity after prolia by an endo i quite liked and i trusted their opinion (second opinion);so i was bothered when i read that the bone preserving effect of evenity after pr*lia isn't quite known. this endo said evenity for 1 year and that the gains are maximal after 9mth then the gains level off after that,

and follow with prolia again.

but i'm reading here and elsewhere that the results with maintaining gains aren't that great ...

i wonder if that means that there's a decline in BMD to start with, with evenity, then upward gains after that?

my Mum's friend had success with a year of evenity after 8 or more years of prolia, so there's that.

[MayGodBlessYou in reply to MayGodBlessYou]

so i asked the 2nd endoif someone came off prolia to start evenity, and if it didn't agree with them the first dose, do you just resume prolia again,

endo said yes,

but my question is then, if there's bone loss due to stopping pr*lia in that month of evenity, then you're behind