I took MTX yesterday morning for the first time, with much trepidation. Absolutely nothing happened except I felt compelled to strip the cushion covers off the sofa & hand wash them in the bath - no nausea, no tiredness, nothing.
I'm still taking Prednisolone & wouldn't be at all surprised if they helped - I gather from other people here that they have lots of useful properties.
Whatever happens I'm glad to have got past this step, it's scary stuff & I hope anyone facing the same thing will take heart from my first DMARD experience. Go easy on the housework, though - that way lies madness.
Let's hope we have some SUN this week, all week preferably xx