methotrexate

[Dexter1414]

does anyone else feel so trierd when taking methotrexate

[helixhelix]

yes, certainly at first. But it improves over time as your body gets used to it.

[Ruth12345]

Yes. Also feel sick and as helixhelix says it does get better. I do find if I'm not feeling great I go back over. However better with than without methotrexate. 🌻

[janmary]

difficult to tell as tiredness is a prominent symptom of the rheumatoid disease itself.

[OSTEOARTHRITISRA]

Yes specially at beginning ,everyone different though Unfortunately Lots also have fatuige long term and med change can be needed for some

[Mostmoses]

Fatigue is a symptom of RA, as others have mentioned. But keep in mind that not everyone does well on methotrexate (I didn't), even though it does work fine for many people. It's basically the first drug to try. Listen to your own body, talk with you doctor, and hopefully you'll find something that works for you. It can take some time.

[HBaaBaa]

yes, for the first 3-4 months of taking it, I always slept for most of the day afterwards. This improved over time though as my body hit used to it. I have just had to have a break for nearly a month due to a nasty virus and am fully expecting that my body will need to get used to taking MTX again and the fatigue will hit tomorrow after my first dose back again tonight.

[PrincessEva]

yes I feel like I’ve been slugged by a brick the next day

[Gramma3]

Yes I am always tired or exhausted especially so, for the first few days. As others have said this can be part of RA as well. Plus I am on Codydramol regularly and Amitriptyline for nerve pain. These all contribute too. I am having my B12 checked in case of pernicious anaemia. If negative, I will just have to live with it. My memory and brain fog is awful too. Very annoying!!

[Hopeful1]

Hi Dexter. Sorry it does tend that way. I drink plenty of water on the dayI take mine and take it last thing at night to sleep off the worst of it.

I expect you have already worked out the best day of the week to take it for you? It is possible to move on 1 day a week till you hit your best (least bad!)day if not already there.

[marie66]

yes, me too but it’s sometimes hard to pinpoint if it’s meds or disease to blame. I definitely find it harder the next day though. I still take an anti sickness med and watch what I eat too. M x

[HeadInASpin]

Pretty much everyone, especially at the beginning. Are you taking folic acid on the six other days of the week? If not then ask for it as it helps a lot.