Hi been on methotrexate tablets for 3 years doc changed it to injection been on them for 9 weeks but started with bowel problemsFirst thing on a morning day after injection
Seems to calm down after a couple of days just wondering if any one else has had the same thanks
Within hours of taking the jab I can feel things rumbling 
Back to normal next day though. So guessing this is fairly common.
Yes although mine was both ends and all the time with ulceration in the mouth as well. Even then the rheumatologist took some convincing!But most people are only mildly affected or not at all. I hope you settle down into a manageable pattern but if not then politely pester until a solution is found.
I had something a bit different. After 6 months of feeling good on methotrexate I started having bad abdominal pain 4 days after the injection, every single time. I stopped for the covid vax and no abdominal pain. I didn't go back onto MTX.
There is something called MTX chronic toxicity which will explain why people can take the drug for a long time before they get symptoms of it building up and being too much.
Hi Conster
Personally, I would stick with it as it passed for me over time. With injections you get more effect from the MTX as you do not lose any from reduction by the digestive route. Especially if MTX is doing a good job on your disease. That is the #1 most important thing to prevent long term damage and other problems. However, if you find it unbearable, then be firm with your clinicians and come off the treatment.
Best wishes
I'm on the tablets and they do give me tummy troubles for a day or so. My rheumy nurse said swapping to injections often helped nausea but not so much the other. It did wear off initially but then when I swapped to GP care I got a different brand of tablets which has set it off again a bit. Increasing the folic acid seems to help.
Knee problems & pregnancy
Benepali problems
Nauseated again 
Methotrexate 
MXT and mouth problems 
