Off topic - vaccine study with RD

[Brushwork]

thelancet.com/journals/lanr...

Worth a read.

[DRunnerchick]

Interesting, but not surprising. I read a study regarding solid organ recipients who were on prednisone (or other anti-rejection drug) and they did not mount a response. I’ll have to find it again if someone wants it for reference. My SIL is a kidney recipient and my cousin’s husband is a liver recipient 🤞🏼🤷‍♀️ I think a third jab is what finally worked for those patients but the study organizers couldn’t recommend it or supply them because of the allocation situation. What a mess this is. I’ll post should my experience and leave this here.😉

D🏃🏽‍♀️

[Madmusiclover in reply to DRunnerchick]

Thank you. As a JAK user with two jabs that is moderately encouraging if I’ve read it correctly. Small study though.

[oldtimer]

Thanks for this reference. Interesting but only a small study. I hope that there are more so that the picture becomes clearer.

[Brushwork in reply to oldtimer]

Me too

[Neonkittie17]

I did read this before and it is encouraging as others have said, but a small trial. I notice it didn’t mention Rtx, (unless I missed it with my blurry specs on!) which is usually mentioned on most of the other vaccine efficacy and RA meds articles. I know JAK’s and a couple of other high spec RA meds are thought to affect the vaccine too. x

[veg_c2000]

Isn't "Methotrexate was used in 28 (53%) patients at a median dose of 15 mg per day" a huge dose? 15 mg per DAY. Does anyone take Methotrexate daily?

V.

[ABwn in reply to veg_c2000]

I'm on a weekly dose and have been from the start.

[BoneyC in reply to veg_c2000]

I thought the same! Surely it should read 'weekly' and not 'daily'?

[Neonkittie17]

I thought 15mgs a day was about mid way for dosage. I was on 25mgs for while before I stopped taking it.

[Boxerlady in reply to Neonkittie17]

I've only ever been on weekly Methotrexate - highest dose 25mg by injection 😕

[Neonkittie17 in reply to Boxerlady]

Yes that was mine at 25mgs sub cut. A doc refused to believe injectable Mtx went above 20mgs so I took him a label to prove it with my name on!

[Boxerlady in reply to Neonkittie17]

Yes - but weekly not daily?!

[Neonkittie17 in reply to Boxerlady]

My apologies .: of course it’s weekly! 😳

[Boxerlady in reply to Neonkittie17]

Phew! 😌😂

[Neonkittie17 in reply to Boxerlady]

I just followed what the person posting above me typed with 15mgs a day and I know they meant a week but I typed day! It could be some people with different reasons for taking Mtx have to have 15mgs daily. x

[Boxerlady in reply to Neonkittie17]

Yes - probably cancer patients

[GinnyE]

Thanks for posting. I took the antibody test from Lloyds to find out if I had responded. I had about 1100 result.