Well the strangest thing happened last night when what started as a little discomfort in my left wrist, turned into the most excruciating pain. I had an X ray this morning and there is a small fracture. What a year it's been, from diagnosis in March, getting a lot of relief from Methotrexate/Hydroxychloroquine combination, then having to stop meds 6 weeks ago because of infections. So now a fracture has come to join the party ! I did trip over a fortnight ago ( never wearing heels again !) so maybe it is from that fall, or else my wrist is just in such a mess that it has fractured spontaneously. Has this happened to anybody else ?