Hi, I'm new to the site; diagnosed with RA in January, hands and wrists badly affected with pain, and my left hand contorting rather. I am a nurse, but have been off sick since March, My consultant started me on oral Methotrexate, but after 2 weeks my liver function tests were so abnormal I had to stop; plus constant nausea, fatigue etc!I converted to injections of MTX, but another 2 weeks, and my LFT was even higher. Plus, feeling even more unwell. On to Sulfasalazine, 3 weeks and my liver was showing real signs of damage (feeling even worse!) So on to Leflunamide; 3 weeks, and my blood tests were better, but my blood pressure was 225/120, very, very scary. Given Cholestyramine sachets to wash out the Leflunamide, 2x3 times a day for 11 days. They were foul, caused constant nausea and diarrhoea, plus blood pressure still frighteningly high, even with added meds to try and bring it down.
My question is, I am now 5 weeks on from finishing the Cholestyramine, am on no RA drugs at all (they haven't worked out the next plan) so pain is a real problem, but still have once or twice daily bouts of nausea and diarrhoea and feel so unwell with this. My blood results are better, but would love to know whether this is going to stop anytime soon. If anyone can give me any advice, I would so welcome it!