Liver enzymes elevated? Not sure if it's the mtx or s... - NRAS

NRAS

36,580 members45,192 posts

Liver enzymes elevated? Not sure if it's the mtx or something else, any advice, pls

ccme98 profile image
4 Replies

Twice I've had elevated liver enzymes, liver biopsy done, twice, no answers as to why, it's a concern because my rheumy, and my GI don't have any answers either, so I get stuck with nausea, leads to vomiting, which then leads to diarrhea, then loss of appetite, loss of weight, and still no answers, I am also on Enbrel, only on 5th injection, what is next, I'm almost to the point of just giving up, any advice as what to do or questions to ask, next appt. is with a new GI..

Thank you

Michelle

Written by
ccme98 profile image
ccme98
To view profiles and participate in discussions please or .
Read more about...
4 Replies
oldtimer profile image
oldtimer

I would want to know: 1, Is it the medication? 2. Is it due to anything else? 3. Can anything be done about it? 4. Does it matter? 5. Do I need to stop the medication when it happens? 6. What alternatives are there?

Jacey15 profile image
Jacey15 in reply to oldtimer

Good list!

Cynthialcj profile image
Cynthialcj

Your liver enzymes are always up..so high you needed a liver biopsy?. Mine have been very high a,few times and went back to normal . I was on arava , a ra drug . Have you been told you have fatty liver..I been on enbril and so far so good with my liver..and I stay away from alcohol and Tylenol products. I definitely would get a,second oponion..just curious if your enzymes are always high. I was told if my liver enzymes got high I'd have to switch meds again..maybe to iv ra med. Just a thought for you to think about from my experience. Good luck

KayEP profile image
KayEP

I had to stop taking MTX as it gave me the liver of an alcoholic (and I don't drink alcohol). I have also used Enbrel for a couple of years until it stopped working and I had a flare up. Enbrel did not effect my liver enzymes, but MTX definitely did. Ask to change MTX for something else. I cannot tolerate several of the DMARDS that the rheumatologist wants me to take as a secondary drug so I just have the one Biologic - at the moment Rituximab and it is working fine at the moment.

You may also like...

Liver Enzymes and RA Advice

have also been plagued since 2002 with elevated liver enzymes, which of course limits the drugs that

Elevated liver enzymes - methotrexate? Asthma inhalers? Overweight?

test on Friday as my last one showed raised liver enzymes. Just got the results and they are raised...

Any advice for coming off mtx against m

consultant wants to increase the dosage to 25mg by injection but has not given me the prescription....

Any advice of MTX side effects will be welcome...

I will be asking my rheumy to go on MTX. This drug has never been offered to me but I think I want...

Liver Problems or something else

has anyone knowledge of symptoms of liver dmage or infection etc my bloods were at 186 last week,...