Today I saw my GP to get paperwork signed so I can go back to work part time. I am feeling so much better now the mtx has kicked in. Anyways my GP said my RA has changed to seronegative. I asked if that was normal. He said he had never heard of it before and that he will talk to my new rheumy about this and get back to me. So....has anyone on this site heard of seopositive turning into seronegative?