I was diagnosed with Ra or Psa last September after swollen painful hands wrists and ankles and put on Mtx 15mg and Folic acid. I seemed to tolerate the regime pretty well but I have had 3 really bad colds in 4 months and I am still suffering with sinus problems blocked nose and ears. After a hospital appointment 3 weeks ago the Mtx was increased to 20mg and 5mg once per day. I was asked to get a blood test to check progress after 2 weeks. I then went to see Doctor to check a couple of things and as I had deer tick exposure last July a blood test was taken in August to check for Lymes Disease but this test had not been done so the Doctor ordered another one. As I also needed a Ha1c blood test to check my Diabetes I thought I would get all the blood tests done at the same time. I had the blood test last Monday and the nurse took my blood pressure and low and behold it was high 175/101, I was asked to go back later that day to get it checked again, it was down but still raised, I am having a BP monitor fitted today. I know my Diabetes check will also be bad because the Arthritis is stopping me exercising. I feel like I am falling apart at the seams. I am not sure whether the BP could have been raised because of the Mtx or Folic acid as my BP is normally good around 130/85. It all seems to be a vicious circle. I really don't want to have to take more tablets. I was awake before 5am again today. It's just getting me down and I am feeling very depressed.