Hello. I'm 23 and just been diagnosed about 3 weeks ago with rheumatoid arthritis.. I'm now on methatrexate once a week and prednisolone daily. I feel like this is going to change the rest of my life and there's nothing I can do about it. I have been having trouble sleeping at night and wake about 4 times a night to pee. Im constantly tired and can hardly bring myself to go to work. Has anyone had these side effects ?