I think I'm writing this to calm my mind and stop the panic. I've been so positive over the last month even with a set back that put me on tramadol again. Things have been warning me however. Today , just now I went shopping and back home all the painkillers I can take are not working and my guts are rebelling with pretty grim pain. So what's the next step here on a Saturday night when nothing is helping ? Ant ideas my friendly support. My husband has gone off to work for the next 5 weeks . I have a lovely daughter nearby but she has ME and is in crash mode just now.