Hi everyone. I was diagnosed in December 2013 with rheumatoid arthritis then affecting 33 joints. I have been given the following medication. Methotrexate 20mg weekly, folic acid, calciferol, plasmaquine, panafcort, cal d, arava, stilpaine, lansoloc, all daily. So this is between 13 to 21 tabs daily. I am apparently responding well to treatment. However im struggling to be active ive played top level sport in SA, I used to cycle every weekend, ive always been physically strong and fit. I am a partner in and audit practise and am currently enrolled for my MSC qualification. All this said I can hardly function these days. Im permanently exhausted and frustrated and have become increasingly moody. Im 36 yr old male. Is this anyone else's experiance?