I just noticed a squishy lump under the ball of my left big toe (metatarsal joint) and I think it may be a Gideons cyst after a quick search online. This comes after three different fingers showing small cysts on dip joints (Wikipedia had a picture of what looked to be the same thing also under the entry for Gideons cyst). I stupidly do not keep full track of this, so am not confident of the timing, but I *think* they have all occurred since changing my medication, and I wonder if it could be related. I went from taking Humira (every 2 weeks) and 7.5 mg meloxicam (NSAID) to doubling the meloxicam and adding 25 mg MTX (weekly) and 400 mg 6x/week of hydroxy (plaquenil). The cysts on my fingers hurt, but the lump under my foot doesn't seem to bother me (though now that i know it's there, I'm nervous about walking on it!).
I promise not to stop my meds if anyone says "it's possible", I just want to know if anyone has experienced this or heard of this possibility.